GLENDALE, Ariz. -- When Andre Ellington heard the final play of Sunday's game called in the huddle, he knew who Carson Palmer's options could be.

When Ellington saw the ball in the air, en route to Larry Fitzgerald, he knew it was going to be a touchdown.

"He makes big plays in big moments," Ellington said.

No one in the Arizona Cardinals' locker room after Fitzgerald's leaping 19-yard touchdown catch gave Arizona an 18-15 win against the San Francisco 49ers in overtime seemed to be surprised or even impressed anymore.

With Fitzgerald, catches like that, at moments like that, are old hat.

"Never surprised," coach Bruce Arians said. "In critical moments, he's like, 'Give me the ball,' and I'm like, 'I'm trying, brother.'"

Fitzgerald is the only active player with multiple overtime receiving touchdowns, including the postseason, according to ESPN Stats & Information.

"He's the best I've ever seen and I've seen some really good ones," Palmer said.

Before the game-winning catch, Fitzgerald was a non-factor in the game.

He had three catches for 13 yards up to that point. It was clear to Palmer that the 49ers had built a game plan around not letting Fitzgerald beat them.

However, on the last play of the game, Palmer saw the 49ers' secondary out of sorts with the safety out of place.

"There was some miscommunication and they weren't doing what they were doing earlier," Palmer said. "There were a couple of guys going back and forth, trying to switch sides, and he just kind of got a free release and was one-on-one up the seam."

Fitzgerald said these types of games happen.

"There's games that you have opportunities and things are going to come your way and you're going to make some plays," he said. "I've played over 200 games now and there's always going to be highs and lows.

"When I was younger, I would get hot about not being involved and things like that, but now, it just doesn't really matter to me, honestly. Ten catches, two catches ... wins. I mean, I just want to win."

Arians said not every pass play is designed to go to Fitzgerald, but because the 49ers blanketed him, "we were drawing some in the dirt for him today.

"The pressure was too much to give it to him at times," Arians added.

But when Palmer looked to Fitzgerald at the most crucial time, Fitzgerald came through.

"When it's his time, it's his time," linebacker Karlos Dansby said. "He's not going to press or anything like that, but we knew at that moment that it was his time. Carson put it up there and he made a play. He's a great player. That's why he's a future Hall of Famer."