The 2025 men's NCAA tournament continues Thursday and Friday with the Sweet 16, and all four No. 1 seeds remain.
So what can we expect in the Sweet 16, and which point spreads and over/unders are worth betting on?
Let's factor in team trends, injuries, momentum and more to identify the smartest wagers to make over the weekend.
Odds are accurate as of publication time. For the latest odds, go to ESPN BET.