Levi's Stadium in Santa Clara, California, will be the site of Super Bowl LX in February. It's also the stage for the latest edition of ESPN's "Monday Night Football."
The San Francisco 49ers welcome the Carolina Panthers for a Week 12 prime-time clash between two teams working to secure a playoff spot. Christian McCaffrey, Brock Purdy and the 49ers (7-4) look to stay hot after scoring a season-high 41 points in a Week 11 road win against the Arizona Cardinals.
Fresh off a franchise-record performance against the Atlanta Falcons, Bryce Young leads the Panthers (6-5) as they seek their third win in four games. Young threw for a Carolina single-game record 448 yards and three scores in a thrilling overtime victory in Atlanta.
The 49ers defeated the Panthers 37-15 in their last meeting on Oct. 9, 2022.
Here are key facts about the Week 12 "Monday Night Football" matchup:
What is the schedule?
*All times Eastern
Monday
3 p.m.: "NFL Live" on ESPN
6 p.m.: "Monday Night Countdown" on ESPN
8:15 p.m.: Panthers at 49ers on ESPN and ABC
8:15 p.m.: "Monday Night Football with Peyton and Eli" -- the "ManningCast" -- on ESPN2
How can fans watch?
Fans can catch all of the action in the ESPN App and in the NFL streaming hub.
New music for 'Monday Night Football'
During the 2025 NFL season, multiplatinum recording artist Saweetie becomes the first woman to be music curator for "Monday Night Football." The Santa Clara, California, native will handpick tracks that will be featured in live "Monday Night Football" broadcasts and promotional spots.
Saweetie joins J Balvin (2024), Timbaland and Justin Timberlake (2023), Marshmello (2022), Drake (2021), DJ Khaled (2020) and Diplo (2019) as ESPN "Monday Night Football" music curators.
How can fans access more NFL content from ESPN?
Check out the ESPN NFL hub page for the latest news, analysis, scores, stats, schedules and more.