THOUSAND OAKS, Calif. -- Los Angeles Rams running back Darrell Henderson suffered a high ankle sprain in the third quarter of Sunday's 20-9 loss to the Seattle Seahawks and will be placed on injured reserve, coach Sean McVay said Monday.
Rams rookie running back Cam Akers also is nursing a high ankle sprain, suffered in Week 15, that kept him inactive against the Seahawks, but McVay said he may be able to return for Sunday's pivotal matchup against the Cardinals.
For the Rams (9-6) to clinch a playoff spot, they must defeat the Cardinals (8-7) at SoFi Stadium or the Green Bay Packers (12-3) must win at the Chicago Bears (8-7).
Veteran running back Malcolm Brown, who has been used mostly in pass protection and goal-line situations this season, could be the only experienced back available if Akers can't play. Brown has rushed for 399 yards and five touchdowns on 98 carries this season.
The Rams also have rookie backs Xavier Jones and Raymond Calais on the roster. Both have contributed on special teams this season.