Week 6 of the College Football season brings one of the most interesting games of the year as the undefeated No. 12 Oklahoma Sooners and No. 3 Texas Longhorns meet for the annual Red River Rivalry at the Cotton Bowl.
In addition to that exciting game, there are three other matchups between Top 25 teams on the Week 6 slate, including No. 23 LSU taking on No. 21 Missouri, the No. 20 Kentucky Wildcats facing a No.3 Georgia Bulldogs team that was almost upset by the Auburn Tigers last weekend. And of course, No. 10 Notre Dame faces the Jeff Brohm's undefeated No. 25 Louisville Cardinals (7:30 p.m. on ABC).
Here are the betting lines, money lines and totals for Week 6 of the college football season.
All odds are courtesy of Caesars Sportsbook.
No. 12 Oklahoma at No. 3 Texas (-6.5)
Saturday, noon PM ET, Cotton Bowl, Dallas, Texas
Money Line: Oklahoma (+210); Texas (-260)
Game Total: 60 points
FPI Favorite: Oklahoma by 1.7 (54.6% chance to win outright)
Betting nuggets
Oklahoma has covered six consecutive games dating back to last season, tied Penn State for the longest active cover streak in FBS.
Oklahoma is 8-2-1 ATS against AP-ranked teams since the start of the 2020 season.
Oklahoma is 3-8 ATS in its last 11 meetings with Texas.
Texas has covered four consecutive Big 12 games.
Maryland at No. 4 Ohio State (-20)
Saturday, noon ET, Ohio Stadium, Columbus, Ohio
Money Line: Maryland (+700); Ohio State (-1100)
Game Total: 57.5 points
FPI Favorite: Ohio State by 20.5 (90.6% chance to win outright)
Betting nuggets
Each of the past eight meetings between Maryland and Ohio State have gone over the total.
Maryland has covered three consecutive games.
11 of Maryland's last 12 games against AP Top-10 teams have gone over the total.
Maryland is 8-21 ATS against AP-ranked teams since the start of the 2016 season.
No. 23 LSU (-6) at No. 21 Missouri
Saturday, noon ET, Memorial Stadium/Faurot Field, Columbia, Missouri
Money Line: LSU (-250); Missouri (+205)
Game Total: 64.5 points
FPI Favorite: LSU by 7.9 (70.3% chance to win outright)
Betting nuggets
LSU has gone over the total in nine consecutive games, the longest active over streak in the FBS.
Missouri is 3-0 ATS as a home underdog since the start of last season.
Each of Missouri's last four October games have gone under the total.
LSU is 1-4 ATS as a road favorite under Brian Kelly.
No. 13 Washington State at UCLA (-3.5)
Saturday, 3 p.m. ET, Rose Bowl, Pasadena, California
Money Line: Washington State (+150); UCLA (-178)
Game Total: 59 points
FPI Favorite: UCLA by 6.3 (66.5% chance to win outright)
Eight of UCLA's nine games against AP-ranked opponents have gone over the total since the start of the 2020 season.
Washington State is 11-4 ATS in its last 15 meetings with UCLA.
Washington State is 2-9 ATS in games off more than six days of rest since the start of the 2019 season.
Washington State is 11-3-1 ATS in October since the start of the 2018 season.
Virginia Tech at No. 5 Florida State (-24)
Saturday, 3:30 p.m. ET, Doak Campbell Stadium, Tallahassee, Florida
Money Line: Virginia Tech (+1250); Florida State (-2800)
Game Total: 53 points
FPI Favorite: Florida State by 26 (94.7% chance to win outright)
Virginia Tech is 1-10 ATS against AP Top-5 teams since the start of the 2005 season.
Virginia Tech is 5-13 ATS on the road since the start of the 2020 season.
Florida State is 3-0 ATS following a bye week since the start of the 2021 season.
Florida State is 9-3 ATS in its last 12 ACC games.
No. 11 Alabama (-2) at Texas A&M
Saturday, 3:30 p.m. ET, Kyle Field, College Station, Texas
Money Line: Alabama (-135); Texas A&M (+115)
Game Total: 49 points
FPI Favorite: Alabama by 6.2 (66.3% chance to win outright)
Betting nuggets
Alabama is 30-15 ATS in the month of October since the start of the 2011 season.
Texas A&M is 3-0-2 ATS against AP-ranked teams since the start of the 2022 season.
Texas A&M is 4-1 ATS this season, tied with Kentucky and Ole Miss for the best cover percentage in the SEC.
Four of the last five meetings between Texas A&M and Alabama have gone over the total.
Syracuse at No. 14 North Carolina (-8)
Saturday, 3:30 p.m. ET, Kenan Stadium, Chapel Hill, North Carolina
Money Line: Syracuse (+270); North Carolina (-345)
Game Total: 59.5 points
FPI Favorite: North Carolina by 4.1 (60.9% chance to win outright)
Syracuse is 0-5 ATS following a straight-up loss since the start of last season.
Syracuse has gone under the total in four consecutive games.
Syracuse is 1-5 ATS in its last six games as an underdog.
North Carolina is 5-12 ATS in games coming off more than six days of rest under Mack Brown.
No. 20 Kentucky at No. 1 Georgia (-14.5)
Saturday, 7 p.m. ET, Sanford Stadium, Athens, Georgia
Money Line: Kentucky (+460); Georgia (-650)
Game Total: 49 points
FPI Favorite: Georgia by 16.5 (86.2% chance to win outright)
Georgia is one of two SEC teams without a cover this season (0-4-1 ATS).
Kentucky is 7-1-1 ATS against AP-ranked teams since the start of the 2021 season. '
Kentucky has covered four consecutive games against Georgia.
Kentucky is 4-1 ATS on the road since the start of last season.
No. 2 Michigan (-19) at Minnesota
Saturday, 7:30 p.m. ET, Huntington Bank Stadium, Minneapolis, Minnesota
Money Line: Michigan (-1400); Minnesota (+800)
Game Total: 46 points
FPI Favorite: Michigan by 17.3 (87.1% chance to win outright)
Each of the last seven meetings between Minnesota and Michigan have gone over the total.
Minnesota is 7-1-2 ATS against AP Top-10 teams since the start of the 2014 season.
Minnesota is 4-0-1 ATS as a double-digit favorite since the start of the 2018 season.
Michigan is 8-2 ATS on the road since the start of the 2021 season.
No. 10 Notre Dame (-6.5) at No. 25 Louisville
Saturday, 7:30 p.m. ET, Cardinal Stadium, Louisville, Kentucky
Money Line: Notre Dame (-260); Louisville (+210)
Game Total: 54 points
FPI Favorite: Notre Dame by 8 (70.6% chance to win outright)
Notre Dame is 11-3 ATS on the road since the start of the 2020 season.
Notre Dame is 6-1-1 ATS against AP-ranked teams since the start of last season.
Louisville has covered each of its last three meetings with Notre Dame.
Louisville is 14-26 ATS as an underdog since the start of the 2016 season.
Arkansas at No. 16 Ole Miss (-11.5)
Saturday, 7:30 p.m. ET, Vaught-Hemingway Stadium, Oxford, Mississippi
Money Line: Arkansas (+335); Ole Miss (-440)
Game Total: 63.5 points
FPI Favorite: Ole Miss by 13.8 (82% chance to win outright)
Arkansas is 9-1 ATS in its last 10 meetings with Ole Miss.
Each of Arkansas' five road games have gone over the total since the start of the 2022 season.
Arkansas is 9-3 ATS over its last 12 games as a road underdog.
Ole Miss is 3-0 ATS at home this season.
Georgia Tech at No. 17 Miami (-21)
Saturday, 8 p.m. ET, Hard Rock Stadium, Miami Gardens, Florida
Money Line: Georgia Tech (+900); Miami (-1600)
Game Total: 57.5 points
FPI Favorite: Miami by 21.8 (91.7% chance to win outright)
Miami is 1-8 ATS following a bye since the start of the 2017 season.
Miami has failed to cover in four consecutive October games.
Georgia Tech has covered four of its last five meetings with Miami.
Georgia Tech is 8-2 ATS in its last 10 games as an underdog.
No. 24 Fresno State (-5.5) at Wyoming
Saturday, 8 p.m. ET, Jonah Field at War Memorial Stadium, Laramie, Wyoming
Money Line: Fresno State (-215); Wyoming (+178)
Game Total: 44.5 points
FPI Favorite: Fresno State by 3.9 (60.4% chance to win outright)
Wyoming has covered each of its last five games against AP-ranked teams dating back to 2016.
Fresno State has covered each of its last five games against Wyoming.
Wyoming is 8-2 ATS as a home underdog since the start of the 2019 season.
Fresno State is 25-11-2 ATS on the road since the start of the 2017 season.
No. 15 Oregon State (-9.5) at California
Saturday, 10 p.m. ET, California Memorial Stadium, Berkeley, California
Money Line: Oregon State (-365); California (+285)
Game Total: 52 points
FPI Favorite: Oregon State by 6.6 (67.4% chance to win outright)
California is 6-1 ATS as a home underdog since the start of the 2020 season.
California is 17-7 ATS as an underdog since the start of the 2019 season.
Oregon State is 11-3 ATS as a favorite since the start of last season.
Oregon State is 3-10 ATS as a road favorite since the start of the 2010 season.
Arizona at No. 9 USC (-21.5)
Saturday, 10:30 p.m. ET, Los Angeles Memorial Coliseum, Los Angeles, California
Money Line: Arizona (+1050); USC (-2000)
Game Total: 72 points
FPI Favorite: USC by 20.7 (90.8% chance to win outright)
Arizona has gone under in five consecutive games, tied with Utah for the longest active under streak in the FBS.
Arizona is 4-0 ATS against AP Top-10 teams since the start of the 2021 season.
Arizona has covered each of its last three games against USC.
USC has gone over the total is nine of its 12 Pac-12 games since the start of last season.