San Francisco 49ers @ Indianapolis Colts
Matchup Predictor
61.0
%
SF
38.7
%
IND
According to ESPN Analytics
Game Information

Season Leaders

2,151
M. JonesQB
201/289, 13 TD, 6 INT
2,151

3,101
D. JonesQBIR
261/384, 19 TD, 8 INT
3,101

922
C. McCaffreyRB
259 CAR, 9 TD
922

1,443
J. TaylorRB
272 CAR, 16 TD
1,443

820
C. McCaffreyRB
86 REC, 5 TD
820

785
A. PierceWRQ
39 REC, 2 TD
785

4
C. FerrellDE
4

6.5
L. LatuDE
6.5

89
D. WintersLB
89

104
Z. FranklinLB
104
Injury Report

| Name | Status | Est. Return |
|---|---|---|
QuestionableAnkle | Dec 22 | |
QuestionableAnkle | Dec 22 | |
QuestionableNeck | Dec 22 | |
QuestionableAnkle | Dec 22 | |
QuestionableAnkle | Dec 22 |

| Name | Status | Est. Return |
|---|---|---|
IR-ROrbital | Dec 28 | |
QuestionableFoot | Dec 22 | |
QuestionableAchilles | Dec 22 | |
QuestionableCalf | Dec 22 | |
IR-RKnee | Dec 22 |
LAST FIVE GAMES
Data is currently unavailable.
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2025 Standings
National Football Conference
| NFC West | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Seattle | 12 | 3 | 0 | .800 | 443 | 279 |
| Los Angeles | 11 | 4 | 0 | .733 | 457 | 299 |
| San Francisco | 10 | 4 | 0 | .714 | 344 | 293 |
| Arizona | 3 | 11 | 0 | .214 | 302 | 388 |
American Football Conference
| AFC South | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Jacksonville | 10 | 4 | 0 | .714 | 376 | 292 |
| Houston | 9 | 5 | 0 | .643 | 323 | 228 |
| Indianapolis | 8 | 6 | 0 | .571 | 392 | 303 |
| Tennessee | 2 | 12 | 0 | .143 | 225 | 394 |
NFL News

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