Game Odds
Odds by
Matchup Predictor
52.2
%
47.4
%
According to ESPN Analytics
Game Information
Lucas Oil Stadium
8:15 PM, December 22, 2025Coverage: ESPN
Indianapolis, IN
Injury Report
San Francisco 49ers| Name, Pos | Status | Est. Return Date |
|---|---|---|
| WR | QUESTIONABLE | Aug 9 |
| RB | QUESTIONABLE | Aug 9 |
| CB | QUESTIONABLE | Aug 9 |
| WR | QUESTIONABLE | Aug 9 |
| WR | PUP-P | Sep 7 |
Indianapolis Colts| Name, Pos | Status | Est. Return Date |
|---|---|---|
| LB | QUESTIONABLE | Aug 7 |
| DT | QUESTIONABLE | Aug 7 |
| CB | IR | Feb 9 |
| DE | QUESTIONABLE | Aug 7 |
| CB | QUESTIONABLE | Aug 7 |
Data is currently unavailable.
Find Tickets
Buy Colts tickets with VividSeats
2025 NFC West Standings
| Team | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Los Angeles | 0 | 0 | 0 | .000 | 0 | 0 |
| Arizona | 0 | 0 | 0 | .000 | 0 | 0 |
| San Francisco | 0 | 0 | 0 | .000 | 0 | 0 |
| Seattle | 0 | 0 | 0 | .000 | 0 | 0 |
2025 AFC South Standings
| Team | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Tennessee | 0 | 0 | 0 | .000 | 0 | 0 |
| Indianapolis | 0 | 0 | 0 | .000 | 0 | 0 |
| Jacksonville | 0 | 0 | 0 | .000 | 0 | 0 |
| Houston | 0 | 0 | 0 | .000 | 0 | 0 |
NFL News