Week 16 gets underway with a huge matchup between NFC West rivals, as the Seattle Seahawks host the Los Angeles Rams on "Thursday Night Football."
And we get another pair of rivalry games Saturday, with the Philadelphia Eagles visiting the Washington Commanders, and the Chicago Bears hosting the Green Bay Packers.
Sunday's slate features big matchups involving the Los Angeles Chargers and Dallas Cowboys, and the Tampa Bay Buccaneers and Carolina Panthers in the early window of games. In the late window, the Jacksonville Jaguars visit the Denver Broncos and the Detroit Lions host the Pittsburgh Steelers.
The New England Patriots hit the road to take on the Baltimore Ravens to close out Sunday's action, and the San Francisco 49ers face off against the recently unretired Philip Rivers and the Indianapolis Colts on "Monday Night Football."
Here's a look at the odds for every Week 16 game.
Note: Odds provided by DraftKings Sportsbook and subject to change. All times Eastern.
Jump to:
LAR-SEA | PHI-WSH | GB-CHI | CIN-MIA
BUF-CLE | TB-CAR | LAC-DAL | KC-TEN
MIN-NYG | NYJ-NO | JAX-DEN | ATL-ARI
PIT-DET | LV-HOU | NE-BAL | SF-IND
Los Angeles Rams vs. Seattle Seahawks -1.5
Thursday, 8:15 p.m., Prime Video
Money Line: Rams (+100); Seahawks (-120)
Total: 42.5; Opened: 47.5
FPI favorite: Rams by 1.4 with a 53% probability to win the game outright
Philadelphia Eagles -7 vs. Washington Commanders
Saturday, 5 p.m., FOX
Money Line: Eagles (-355); Commanders (+280)
Total: 44.5; Opened: 45.5
FPI favorite: Eagles by 6.8 with a 68% probability to win the game outright
Green Bay Packers -1.5 vs. Chicago Bears
Saturday, 8:20 p.m., FOX
Money Line: Packers (-110); Bears (-110)
Total: 46.5; Opened: 46.5
FPI favorite: Packers by 3.3 with a 58% probability to win the game outright
Cincinnati Bengals -4.5 vs. Miami Dolphins
Sunday, 1 p.m., CBS
Line movement: Opened Bengals -1.5
Money Line: Bengals (-205); Dolphins (+170)
Total: 47.5; Opened: 50.5
FPI favorite: Bengals by 8 with a 70% probability to win the game outright
Buffalo Bills -10.5 vs. Cleveland Browns
Sunday, 1 p.m., CBS
Line movement: Opened Bills -8.5
Money Line: Bills (-675); Browns (+490)
Total: 41.5; Opened: 42.5
FPI favorite: Bills by 12.8 with a 80% probability to win the game outright
Tampa Bay Buccaneers -3 vs. Carolina Panthers
Sunday, 1 p.m., FOX
Money Line: Buccaneers (-155); Panthers (+130)
Total: 45.5; Opened: 45.5
FPI favorite: Buccaneers by 2.3 with a 57% probability to win the game outright
Los Angeles Chargers vs. Dallas Cowboys -2.5
Sunday, 1 p.m., FOX
Money Line: Chargers (+110); Cowboys (-130)
Total: 49.5; Opened: 48.5
FPI favorite: Chargers by 0.5 with a 52% probability to win the game outright
Kansas City Chiefs -3 vs. Tennessee Titans
Sunday, 1 p.m., CBS
Line movement: Opened Chiefs -11.5
Money Line: Chiefs (-175); Titans (+145)
Total: 37.5; Opened: 41.5
FPI favorite: Chiefs by 6.9 with a 69% probability to win the game outright
Minnesota Vikings -3 vs. New York Giants
Sunday, 1 p.m., FOX
Money Line: Vikings (-148); Giants (+124)
Total: 43.5; Opened: 43.5
FPI favorite: Giants by 2 with a 55% probability to win the game outright
New York Jets vs. New Orleans Saints -5.5
Sunday, 1 p.m., CBS
Line movement: Opened Saints -3.5
Money Line: Jets (+205); Saints (-250)
Total: 40.5; Opened: 40.5
FPI favorite: Saints by 10.9 with a 76% probability to win the game outright
Jacksonville Jaguars vs. Denver Broncos -3
Sunday, 4:05 p.m., FOX
Money Line: Jaguars (+136); Broncos (-162)
Total: 47.5; Opened: 43.5
FPI favorite: Broncos by 2.9 with a 58% probability to win the game outright
Atlanta Falcons -3 vs. Arizona Cardinals
Sunday, 4:05 p.m., FOX
Line movement: Opened Cardinals -1.5
Money Line: Falcons (-155); Cardinals (+130)
Total: 48.5; Opened: 46.5
FPI favorite: Cardinals by 1.4 with a 53% probability to win the game outright
Pittsburgh Steelers vs. Detroit Lions -7
Sunday, 4:25 p.m., CBS
Money Line: Steelers (+275); Lions (-345)
Total: 51.5; Opened: 49.5
FPI favorite: Lions by 6.6 with a 67% probability to win the game outright
Las Vegas Raiders vs. Houston Texans -14.5
Sunday, 4:25 p.m., CBS
Line movement: Opened Texans -12.5
Money Line: Raiders (+750); Texans (-1200)
Total: 37.5; Opened: 37.5
FPI favorite: Texans by 13.1 with a 80% probability to win the game outright
New England Patriots vs. Baltimore Ravens -3
Sunday, 8:20 p.m., NBC, Peacock
Money Line: Patriots (+136); Ravens (-162)
Total: 48.5; Opened: 48.5
FPI favorite: Ravens by 3.9 with a 61% probability to win the game outright
San Francisco 49ers -6 vs. Indianapolis Colts
Monday, 8:15 p.m., ESPN, ABC
Money Line: 49ers (-290); Colts (+235)
Total: 46.5; Opened: 45.5
FPI favorite: 49ers by 4.3 with a 61% probability to win the game outright