Fantasy baseball lineup advice and betting tips for Wednesday

ESPN Fantasy

Jun 24, 2025, 02:22 PM ET

Check out all of our starting pitcher rankings and other lineup selection tools here to help you make smart fantasy baseball lineup decisions. MLB betting tips for each day's slate of games will also be added in the morning. MLB game odds are provided by ESPN BET, and all fantasy advice is geared toward ESPN 10-team leagues with standard scoring.

Note: All information is accurate as of the time of publication. For updates, including what you might have missed from last night, as well as any breaking news that might impact today's MLB slate, be sure to check out the latest fantasy baseball news.

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STARTING PITCHERS FOR WEDNESDAY

Pitchers are ranked in order of their Forecaster/Daily Notes projected fantasy points (FPTS), using ESPN's standard scoring system (2 points per win, minus-2 per loss, 3 per inning, 1 per K, minus-1 apiece per hit or walk allowed, minus-2 per earned run allowed).

T: The pitcher's handedness. OPP: Opposing team. RST%: The pitcher's roster percentage in ESPN leagues. ML: ESPN BET Money Line. O/U: ESPN BET Over/Under for runs scored. For the projected stat line, W% is the team's win probability using ESPN projections, IP is innings pitched, ER is earned runs allowed and K is strikeouts.

If a team is planning on using an "opener" to start their game, but will rely on a "bulk pitcher" to follow him on the mound after 1-2 innings, the bulk pitcher is listed and indicated with an asterisk.

FPTS	Pitcher	T	Opp	Rst%	W%	IP	ER	K
16.9	Zack Wheeler	R	@HOU	99.9%	63%	6.4	1.8	7.1
14.2	Paul Skenes	R	@MIL	99.9%	63%	5.9	2.0	6.5
12.4	Nick Pivetta	R	WSH	90.0%	62%	5.6	2.1	6.0
12.0	Logan Webb	R	MIA	99.1%	61%	6.2	2.5	5.6
11.0	Clay Holmes	R	ATL	76.2%	60%	5.6	2.1	5.1
10.6	MacKenzie Gore	L	@SD	91.8%	38%	5.5	2.2	5.8
10.6	Joe Ryan	R	SEA	97.3%	53%	5.4	2.7	6.2
10.5	Zac Gallen	R	@CWS	73.5%	59%	5.7	2.6	5.8
10.5	Matthew Boyd	L	@STL	58.1%	54%	5.3	2.0	4.9
10.3	George Kirby	R	@MIN	76.5%	47%	5.7	2.7	5.5
10.3	Jacob deGrom	R	@BAL	97.2%	57%	5.1	2.2	5.3
10.1	Erick Fedde	R	CHC	10.7%	46%	5.6	2.3	5.1
9.8	Max Fried	L	@CIN	99.5%	56%	5.5	2.7	6.1
9.8	Max Scherzer	R	@CLE	12.6%	52%	5.2	2.5	5.5
9.6	Jack Flaherty	R	ATH	79.8%	50%	5.5	3.0	6.2
8.8	Yusei Kikuchi	L	BOS	63.6%	47%	5.5	3.0	6.0
8.3	Brady Singer	R	NYY	32.3%	44%	5.6	3.1	5.4
8.1	Colton Gordon	L	PHI	1.3%	37%	5.3	2.8	5.1
7.9	Didier Fuentes	R	@NYM	0.5%	40%	4.7	2.1	4.7
7.9	Jacob Lopez	L	@DET	2.9%	50%	5.0	2.6	5.1
7.9	Edward Cabrera	R	@SF	5.0%	39%	4.8	2.2	4.8
7.3	Michael Wacha	R	TB	25.3%	55%	5.4	3.1	4.7
7.1	Gavin Williams	R	TOR	18.4%	48%	5.0	2.7	4.8
6.9	Jacob Misiorowski	R	PIT	66.0%	37%	4.5	2.3	5.2
6.2	Sean Burke	R	ARI	2.2%	41%	5.1	3.0	4.8
6.1	Drew Rasmussen	R	@KC	71.1%	45%	4.3	2.3	3.7
5.9	Tomoyuki Sugano	R	TEX	13.9%	43%	5.3	3.2	4.2
4.9	Yoshinobu Yamamoto	R	@COL	99.4%	63%	5.5	4.9	6.3
4.2	Richard Fitts	R	@LAA	0.5%	53%	4.1	2.6	3.3
-2.7	Chase Dollander	R	LAD	1.3%	37%	4.3	5.6	4.1

Pitchers to stream on Wednesday

Max Scherzer is slated to rejoin the Toronto Blue Jays' rotation after missing over three months with a right thumb issue. He's still not fully healed, but he's to the point he can manage the problem without a significant workload concern. Scherzer started two games on rehab, tossing 4 1/3 innings in each, though he struck out eight while yielding just one hit and no runs in his last outing. Scherzer is on the road against a pesky, but not especially potent Cleveland Guardians lineup, sporting the fifth lowest wOBA facing right-handers.
Normally, streaming against the Arizona Diamondbacks is risky considering they boast the second highest wOBA with a righty on the hill. However, they'll be without two, and perhaps four of their better hitters when Sean Burke and the Chicago White Sox hook up in Rate Field. The guests will be without Corbin Carroll and Gabriel Moreno and may also be missing Josh Naylor and Eugenio Suarez. Burke's 4.50 ERA and 1.42 WHIP may seem worrisome, but he's registered six quality starts, three coming in his last five efforts and fanned 28 in his 28 most recent innings.
Streaming recommendations are usually reserved for starters available in more than half of ESPN leagues, but considering the circumstances, Jacob Misiorowski and his 66% ESPN rostership deserves a mention. The Milwaukee Brewers host the Pittsburgh Pirates with Paul Skenes taking the hill. Hopefully, this is the first of many matchups between the NL Central young aces. Well, calling Misiorowski an ace is a bit premature, but he's headed in that direction. The 23-year-old righty yielded just one total hit in his first two starts, covering 11 innings. Control is an issue as his five walks shows, but Misiorowski fanned 11 and has the potential to be more dominant. On Wednesday, Misiorowski faces the offense with the second lowest wOBA versus right-handers.

Pitchers to avoid on Wednesday

Yusei Kikuchi has righted the ship, at least in terms of strikeouts with 19 over his previous two starts spanning 12 2/3 innings. However, he surrendered two homers and five earned runs, so he's a risk at home against the Boston Red Sox and their platoon-heavy lineup. The visitors tote the second best wOBA versus lefties into Angels Stadium.

Hitters to stream on Wednesday

Los Angeles Dodgers 3B Max Muncy and his 46% fly ball rate is ideal for Coors Field. The Colorado Rockies will send Chase Dollander to the hill in the NL West matchup. On another team, Dollander would have more appeal, but so far the talented rookie has struggled at home, serving up eight homers in just 20 1/3 home innings. Muncy is in a great spot to pad his home run total.

Betting tips

Best/worst pitcher/hitter matchups and betting projections are generated by THE BAT X, a system created by Derek Carty using advanced methods like those used in MLB front offices, accounting for a variety of factors including player talent, ballparks, bullpens, weather, umpires, defense, catcher pitch-framing, and lots more. Betting projections for every player, team, and game can be found at EV Analytics.

Note: Expected Value is a measure of how good a bet is, factoring the probability that it will win versus the odds the book is providing. If you were to wager $1.00 100 times on a bet with an Expected Value of $25, you would win some and you would lose some, but in the end you would expect to come away with $25 in profit on your $100 investment.

Because odds typically do not get set until the previous day's games are completed, betting tips will be added in the morning.