Week 12 gets underway with the Buffalo Bills visiting the Houston Texans as road favorites on "Thursday Night Football."
Sunday afternoon gives us several intriguing games, with the AFC North-leading Pittsburgh Steelers taking on the NFC North-leading Chicago Bears (-3) at Soldier Field and the Indianapolis Colts hitting the road to face the Kansas City Chiefs (-3.5) in the early round of games. The late window features a matchup of NFC East rivals when the Dallas Cowboys host the Philadelphia Eagles (-4.5).
The Tampa Bay Buccaneers and Los Angeles Rams (-6.5), both tops in their respective divisions, close out the slate on "Sunday Night Football," and the week wraps up with the Carolina Panthers visiting the San Francisco 49ers (-6.5) on "Monday Night Football."
The Denver Broncos, Miami Dolphins, Los Angeles Chargers and Washington Commanders have a bye this week. Here's a look at the odds for every Week 12 game.
Note: Odds at time of publication, courtesy of ESPN BET Sportsbook.
Jump to:
BUF-HOU | PIT-CHI | IND-KC | NYG-DET
MIN-GB | NE-CIN | NYJ-BAL | SEA-TEN
JAX-ARI | CLE-LV | PHI-DAL | ATL-NO
TB-LAR | CAR-SF


Buffalo Bills -4.5 vs. Houston Texans
Thursday, 8:15 p.m., Prime Video
Money line: Bills (-250); Texans (+210)
Total: 43.5; Opened: 44.5
FPI favorite: Bills by 0.6 with a 53% probability to win the game outright

Pittsburgh Steelers vs. Chicago Bears -3
Sunday, 1 p.m., CBS
Money line: Steelers (+130); Bears (-150)
Total: 45.5; Opened: 45.5
FPI favorite: Bears by 0.1 with a 50% probability to win the game outright

Indianapolis Colts vs. Kansas City Chiefs -3.5
Sunday, 1 p.m., CBS
Money line: Colts (+140); Chiefs (-165)
Total: 50.5; Opened: 50.5
FPI favorite: Chiefs by 4.4 with a 62% probability to win the game outright

New York Giants vs. Detroit Lions -10.5
Sunday, 1 p.m., Fox
Money line: Giants (+425); Lions (-650)
Total: 50.5; Opened: 50.5
FPI favorite: Lions by 8.5 with a 71% probability to win the game outright

Minnesota Vikings vs. Green Bay Packers -6.5
Sunday, 1 p.m., Fox
Money line: Vikings (+240); Packers (-290)
Total: 41.5; Opened: 42.5
FPI favorite: Packers by 8.6 with a 71% probability to win the game outright

New England Patriots -7.5 vs. Cincinnati Bengals
Sunday, 1 p.m., CBS
Line movement: Opened Patriots -5.5
Money line: Patriots (-380); Bengals (+290)
Total: 50.5; Opened: 50.5
FPI favorite: Patriots by 3.4 with a 59% probability to win the game outright

New York Jets vs. Baltimore Ravens -14
Sunday, 1 p.m., CBS
Money line: Jets (+750); Ravens (-1400)
Total: 44.5; Opened: 44.5
FPI favorite: Ravens by 12.6 with an 80% probability to win the game outright

Seattle Seahawks -13 vs. Tennessee Titans
Sunday, 1 p.m., Fox
Money line: Seahawks (-900); Titans (+550)
Total: 40.5; Opened: 42.5
FPI favorite: Seahawks by 10.7 with a 76% probability to win the game outright

Jacksonville Jaguars -2.5 vs. Arizona Cardinals
Sunday, 4:05 p.m., CBS
Money line: Jaguars (-140); Cardinals (+120)
Total: 48.5; Opened: 47.5
FPI favorite: Jaguars by 1.7 with a 54% probability to win the game outright

Cleveland Browns vs. Las Vegas Raiders -3
Sunday, 4:05 p.m., CBS
Money line: Browns (+135); Raiders (-155)
Total: 37.5; Opened: 37.5
FPI favorite: Raiders by 5.8 with a 65% probability to win the game outright

Philadelphia Eagles -4.5 vs. Dallas Cowboys
Sunday, 4:25 p.m., Fox
Money line: Eagles (-230); Cowboys (+195)
Total: 50.5; Opened: 51.5
FPI favorite: Eagles by 3.2 with a 58% probability to win the game outright

Atlanta Falcons vs. New Orleans Saints -1.5
Sunday, 4:25 p.m., Fox
Line movement: Opened Falcons -3
Money line: Falcons (-105); Saints (-115)
Total: 38.5; Opened: 40.5
FPI favorite: Falcons by 1.6 with a 55% probability to win the game outright

Tampa Bay Buccaneers vs. Los Angeles Rams -6.5
Sunday, 8:20 p.m., NBC, Peacock
Money line: Buccaneers (+250); Rams (-300)
Total: 49.5; Opened: 49.5
FPI favorite: Rams by 5.5 with a 64% probability to win the game outright

Carolina Panthers vs. San Francisco 49ers -6.5
Monday, 8:15 p.m., ESPN
Money line: Panthers (+260); 49ers (-320)
Total: 47.5; Opened: 47.5
FPI favorite: 49ers by 9.2 with a 73% probability to win the game outright
