There are four ranked matchups this week across the college football landscape, including the biggest test thus far for No. 6 Oregon and No. 3 Penn State. Oregon entered last year's College Football Playoff as the No. 1 seed before falling in the quarterfinals to Ohio State. Penn State made the semifinals before falling to Notre Dame. Both teams enter this matchup with championship ambitions, and have played up to expectations thus far. ESPN College Gameday will broadcast live from Happy Valley at 12 noon ET.
There are two ranked matches in the SEC, back-to-back on ABC. The No. 4 LSU face No. 13 Ole Miss in Oxford and the No. 17 Alabama take on No. 5 Georgia in Athens immediately after.
The state of Texas has three teams in the top-12 of the AP Poll (No. 9 Texas A&M, No. 10 Texas and No. 12 Texas Tech after their win over Utah) for the first time since 2016, according to ESPN Research.
All times Eastern. For latest lines, go to ESPN BET
No. 8 Florida State -7.5 at Virginia
Friday, 7 p.m., ESPN
Records: Florida State 3-0, 1-0 vs. AP teams; Virginia 3-1, 0-0 vs. AP teams
Opening Line: Florida State -7.5, O/U 51.5
Money line: Florida State (-290); Virginia (+240)
Over/Under: 58.5 (O -110, U 110)
FPI Projection Florida State by 2.5 points with a 60% probability to win game outright
No. 24 TCU at Arizona State -2.5
Friday, 9 p.m., FOX
Records: TCU 3-0, 0-0 vs. AP teams; Arizona State 3-1, 0-0 vs. AP teams
Opening Line: Arizona State -1.5, O/U 56.5
Money line: TCU (+115); Arizona State (-135)
Over/Under: 55.5 (O EVEN, U 120)
FPI Projection TCU by 0.1 points with a 51% probability to win game outright
No. 16 Georgia Tech -14.5 at Wake Forest
Saturday, Noon, ESPN
Records: Georgia Tech 4-0, 1-0 vs. AP teams; Wake Forest 2-1, 0-0 vs. AP teams
Opening Line: Georgia Tech -14.5, O/U 53.5
Money line: Georgia Tech (-700); Wake Forest (+450)
Over/Under: 53.5 (O -105, U 115)
FPI Projection Georgia Tech by 11.7 points with a 84% probability to win game outright
No. 21 USC -7.5 at No. 23 Illinois
Saturday, Noon, FOX
Records: USC 4-0, 0-0 vs. AP teams; Illinois 3-1, 0-1 vs. AP teams
Line Movement Alert: Opened USC -1.5, O/U 56.5
Money line: USC (-260); Illinois (+215)
Over/Under: 59.5 (O -115, U 105)
FPI Projection USC by 6.3 points with a 73% probability to win game outright
No. 22 Notre Dame -4.5 at Arkansas
Saturday, Noon, ABC
Records: Notre Dame 1-2, 0-2 vs. AP teams; Arkansas 2-2, 0-1 vs. AP teams
Opening Line: Notre Dame -6.5, O/U 58.5
Money line: Notre Dame (-200); Arkansas (+170)
Over/Under: 64.5 (O -105, U -115)
FPI Projection Notre Dame by 1.4 points with a 56% probability to win game outright
Utah State at No. 18 Vanderbilt -21.5
Saturday, 12:45 p.m., SEC Network
Records: Utah State 3-1, 0-1 vs. AP teams; Vanderbilt 4-0, 1-0 vs. AP teams
Opening Line: Vanderbilt -21.5, O/U 59.5
Money line: Utah State (+1000); Vanderbilt (-2000)
Over/Under: 59.5 (O -110, U -110)
FPI Projection Vanderbilt by 22.7 points with a 94% probability to win game outright
No. 1 Ohio State -9.5 at Washington
Saturday, 3:30 p.m., CBS, Paramount+
Records: Ohio State 3-0, 1-0 vs. AP teams; Washington 3-0, 0-0 vs. AP teams
Line Movement Alert: Opened Ohio State -13.5, O/U 48.5
Money line: Ohio State (-360); Washington (+280)
Over/Under: 52.5 (O -110, U -110)
FPI Projection Ohio State by 5 points with a 69% probability to win game outright
No. 4 LSU -2.5 at No. 13 Ole Miss
Saturday, 3:30 p.m., ABC
Records: LSU 4-0, 1-0 vs. AP teams; Ole Miss 4-0, 0-0 vs. AP teams
Opening Line: LSU -1.5, O/U 56.5
Money line: LSU (+110); Ole Miss (-130)
Over/Under: 55.5 (O -110, U -110)
FPI Projection Ole Miss by 6.5 points with a 73% probability to win game outright
Auburn at No. 9 Texas A&M -6.5
Saturday, 3:30 p.m., ESPN
Records: Auburn 3-1, 0-1 vs. AP teams; Texas A&M 3-0, 1-0 vs. AP teams
Opening Line: Texas A&M -6.5, O/U 46.5
Money line: Auburn (+210); Texas A&M (-250)
Over/Under: 52.5 (O -115, U -105)
FPI Projection Texas A&M by 4.7 points with a 68% probability to win game outright
No. 11 Indiana -7.5 at Iowa
Saturday, 3:30 p.m., Peacock
Records: Indiana 4-0, 1-0 vs. AP teams; Iowa 3-1, 0-1 vs. AP teams
Line Movement Alert: Opened Indiana -3.5, O/U 48.5
Money line: Indiana (-275); Iowa (+225)
Over/Under: 48.5 (O -115, U -105)
FPI Projection Indiana by 8.7 points with a 78% probability to win game outright
No. 15 Tennessee -7.5 at Mississippi State
Saturday, 4:15 p.m., SEC Network
Records: Tennessee 3-1, 0-1 vs. AP teams; Mississippi State 4-0, 1-0 vs. AP teams
Opening Line: Tennessee -9.5, O/U 61.5
Money line: Tennessee (-290); Mississippi State (+240)
Over/Under: 61.5 (O -120, U EVEN)
FPI Projection Tennessee by 6.5 points with a 74% probability to win game outright
Arizona at No. 14 Iowa State -6.5
Saturday, 7 p.m., ESPN
Records: Arizona 3-0, 0-0 vs. AP teams; Iowa State 4-0, 1-0 vs. AP teams
Opening Line: Iowa State -7.5, O/U 49.5
Money line: Arizona (+200); Iowa State (-240)
Over/Under: 50.5 (O -115, U -105)
FPI Projection Iowa State by 2.8 points with a 61% probability to win game outright
No. 6 Oregon at No. 3 Penn State -3.5
Saturday, 7:30 p.m., NBC, Peacock
Records: Oregon 4-0, 0-0 vs. AP teams; Penn State 3-0, 0-0 vs. AP teams
Opening Line: Penn State -3.5, O/U 53.5
Money line: Oregon (+150); Penn State (-175)
Over/Under: 52.5 (O -105, U -115)
FPI Projection Penn State by 0.3 points with a 51% probability to win game outright
No. 17 Alabama at No. 5 Georgia -2.5
Saturday, 7:30 p.m., ABC
Records: Alabama 2-1, 0-0 vs. AP teams; Georgia 3-0, 1-0 vs. AP teams
Opening Line: Georgia -3.5, O/U 53.5
Money line: Alabama (+125); Georgia (-145)
Over/Under: 53.5 (O -105, U -115)
FPI Projection Georgia by 1.1 points with a 55% probability to win game outright
Massachusetts at No. 20 Missouri -44.5
Saturday, 7:30 p.m., ESPNU
Records: Massachusetts 0-3, 0-0 vs. AP teams; Missouri 4-0, 0-0 vs. AP teams
Opening Line: Missouri -43.5, O/U 55.5
Money line: Off
Over/Under: 56.5 (O -110, U -110)
FPI Projection Missouri by 44.5 points with a >99% probability to win game outright
No. 25 BYU -6.5 at Colorado
Saturday, 10:15 p.m., ESPN
Records: BYU 3-0, 0-0 vs. AP teams; Colorado 2-2, 0-0 vs. AP teams
Opening Line: BYU -6.5, O/U 47.5
Money line: BYU (-250); Colorado (+210)
Over/Under: 47.5 (O -105, U -115)
FPI Projection BYU by 8.1 points with a 77% probability to win game outright