Week 3 of the NFL season wraps up with the Baltimore Ravens playing host to the Detroit Lions on "Monday Night Football."
The Ravens trounced the Browns in Week 2 to move to 1-1, and the Lions blew out the Bears to even their record.
Baltimore is a 4.5-point favorite for Monday's game, with the total sitting at 53.5, the highest of the week.
From odds and trends to picks, props and analysis from our experts, here's everything you need to help make your decisions at the betting window.
Note: Odds at time of publication. For the latest updates, visit ESPN BET. 
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Game picks | Prop bets | Betting trends
Game bets
Maldonado: Detroit made a statement with a 52-point outburst in Week 2, but this road trip to Baltimore is different. The Ravens lead the NFL in explosive play rate, with over a quarter of their snaps going for 10-plus yards. Keep pace. The bigger mismatch is that Lamar Jackson has been elite when not being pressured, and Detroit ranks 26th in pressure rate. Add Derrick Henry facing a defense allowing 4.7 YPC, and Baltimore has the edge.
Notable player props, bets
Dan Orlovsky and Adam Schefter debate which offense will dominate as Lamar Jackson and the Ravens meet the Lions head-to-head Monday night.
Lamar Jackson 2+ passing TDs and Derrick Henry anytime TD (+129)
Maldonado: I love this combo. The Lions blitz a ton but are bottom five in pressure rate, which is basically begging Jackson to carve them up when he's clean. He's sitting at 9.5 yards per attempt with an 18% touchdown rate in those spots (the league average is around 4-5%). It's a small early-season sample, but it highlights just how dangerous Jackson has been when teams don't get home with pressure. Add in Henry against a defense that has allowed a rushing touchdown in both games this year while giving up almost 5 yards a carry, and you've got the perfect one-two punch. Lamar through the air, Henry at the goal line.
Jameson Williams to go OVER 49.5 receiving yards (-120)
Loza: Williams has long been considered a high-ceiling player. Given his 4.39 speed, that makes sense. His lack of volume (currently, nine targets, WR58) and his YPR (21.8 after two games, WR2) make his production difficult to project. Still, with the Lions 4.5-point underdogs in a game with the highest projected point total for the week (53.5), Williams figures to be integral in John Morton's offensive plan. There's no way he's not drawing deep looks while trading blows with the Ravens.
Jameson Williams' longest reception OVER 23.5 yards (-110)
Bowen: Williams had two receptions of 40 or more yards in the Week 2 win over the Bears, and he'll see heavy split-safety coverage from the Ravens on Monday night (49.5% of coverage snaps). Here, the Lions can scheme for Williams on vertical-shot plays to create explosive opportunities.
Betting trends
Courtesy of ESPN Research
The Lions are 14-4 against the spread in road games since 2023.
Dan Campbell is 52-30 ATS, the best mark of any coach since the 1970 AFL/NFL merger (min. 15 games).
Lamar Jackson is 24-2 in his career against NFC teams, with the only losses coming against the Giants in 2022 and the Eagles last season.
The Ravens are 5-1 ATS in their past six overall as a favorite and 3-0 ATS in their past three as a home favorite.