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Women's March Madness 2025: Best bets for the Final Four

UCLA's Lauren Betts has an advantage over UConn in the paint, but the Huskies like to shoot it from deep. James Snook-Imagn Images

The women's Final Four features three No. 1 seeds (South Carolina, UCLA and Texas) and one No. 2 seed (UConn) and has the makings of an electric finish in the days ahead.

So, which bets make the most sense for Friday's games? And what other betting angles stand out?

Let's factor in team trends, injuries, momentum and more to identify the smartest wagers to make.

Odds are accurate as of publication time. For the latest odds, go to ESPN BET.

South Carolina Gamecocks vs. Texas Longhorns, 7 p.m. ET
Bet: South Carolina team total over 64.5

When these teams first met in January, the over/under for the game was 145.5. It was 135.5 and 133.5 for the last two meetings, and now it's all the way down to 124.5, a drastic move in market perception in a couple of months. All three meetings went under, but Texas was the primary culprit, averaging 53.7 points per game. This seems like a buy-low spot on the total, especially on the South Carolina side, as it is the lowest team total in any Gamecocks game all season.

UCLA Bruins vs. UConn Huskies, 9 p.m. ET
Bet: Over 135.5

Both offenses have been on fire shooting threes all tournament, with UConn averaging 10.3 per game and UCLA at 8.5. UConn's perimeter shooting should come in handy against a UCLA defense led by Lauren Betts in the middle. Betts is coming off a six-block game against LSU, but if UConn keeps shooting like they have been, her rim protection is negated. On the other side, Betts has an edge on the interior against UConn's bigs, and UCLA has plenty of firepower around her. If UCLA can keep this relatively competitive, this game should go over the total.