There are 16 games on the Week 17 schedule and they're spread out over five days of football and eight stand-alone games, beginning Christmas Day with the Kansas City Chiefs at the Pittsburgh Steelers and the Baltimore Ravens at the Houston Texans. While all four teams have clinched a playoff berth, the Chiefs will be looking to clinch the AFC and home field throughout the playoffs while the Steelers and Ravens are battling for the AFC North title, both teams having a 10-5 record and having split their season series.
Thursday's game will have the Chicago Bears hosting the Seattle Seahawks who are still in the hunt for the NFC West title, one game behind the Los Angeles Rams, who they will face in Week 18.
Those same Rams are in action on Saturday, hosting the Arizona Cardinals in the nightcap of a three-game slate that will kick off with the Los Angeles Chargers at the New England Patriots followed by the Denver Broncos at the Cincinnati Bengals.
The Sunday night prime-time game will have the Washington Commanders hosting the Atlanta Falcons while "Monday Night Football" sees the Detroit Lions paying a visit to the San Francisco 49ers in a game that opened with the week's highest total at 51.5.
Here are the lines, spreads and totals for all 16 games on the Week 17 slate. Football Power Index (FPI) by ESPN Analytics. All times listed as Eastern. Odds current as of publication. For the most current odds go to ESPN BET
Kansas City Chiefs -3 vs. Pittsburgh Steelers
Wednesday, 1 p.m., Netflix
Money Line: Chiefs (-155) ; Steelers (+135)
Total: 43.5; Opened: 43.5
FPI favorite: Chiefs by 2.2, 55.5% to win outright
Baltimore Ravens -5 vs. Houston Texans
Wednesday, 4:30 p.m., Netflix
Money Line: Ravens (-230) ; Texans (+195)
Total: 46.5; Opened: 47.5
FPI favorite: Ravens by 4.8, 62.8% to win outright
Seattle Seahawks -3.5 vs. Chicago Bears
Thursday, 8:15 p.m., Prime Video
Money Line: Seahawks (-190) ; Bears (+160)
Total: 43.5; Opened: 42.5
FPI favorite: Bears by 0, 49.8% to win outright
Los Angeles Chargers -4 vs. New England Patriots
Saturday, 1 p.m., NFL Net
Money Line: Chargers (-200) ; Patriots (+170)
Total: 42.5; Opened: 42.5
FPI favorite: Chargers by 3.9, 61.8% to win outright
Denver Broncos vs. Cincinnati Bengals -3.5
Saturday, 4:30 p.m., NFL Net
Money Line: Broncos (+145) ; Bengals (-170)
Total: 49.5; Opened: 48.5
FPI favorite: Bengals by 2.7, 57.3% to win outright
Arizona Cardinals vs. Los Angeles Rams -6
Saturday, 8 p.m., NFL Net
Money Line: Cardinals (+215) ; Rams (-260)
Total: 48.5; Opened: 48.5
FPI favorite: Rams by 2.1, 55.7% to win outright
New York Jets vs. Buffalo Bills -10
Sunday, 1 p.m., CBS
Money Line: Jets (+360) ; Bills (-500)
Total: 46.5; Opened: 47.5
FPI favorite: Bills by 8.6, 71.3% to win outright
Carolina Panthers vs. Tampa Bay Buccaneers -8
Sunday, 1 p.m., CBS
Money Line: Panthers (+320) ; Buccaneers (-425)
Total: 49.5; Opened: 48.5
FPI favorite: Buccaneers by 12.8, 80.5% to win outright
Indianapolis Colts -8 vs. New York Giants
Sunday, 1 p.m., FOX
Money Line: Colts (-425) ; Giants (+320)
Total: 40.5; Opened: 40.5
FPI favorite: Colts by 4.6, 61.3% to win outright
Dallas Cowboys vs. Philadelphia Eagles -9
Sunday, 1 p.m., FOX
Money Line: Cowboys (+340) ; Eagles (-450)
Total: 43.5; Opened: 42.5
FPI favorite: Eagles by 10.9, 76.4% to win outright
Las Vegas Raiders vs. New Orleans Saints -1
Sunday, 1 p.m., FOX
Money Line: Raiders (+100) ; Saints (-120)
Total: 39.5; Opened: 39.5
FPI favorite: Raiders by 2.7, 57.5% to win outright
Tennessee Titans vs. Jacksonville Jaguars -1
Sunday, 1 p.m., CBS
Money Line: Titans (+100) ; Jaguars (-120)
Total: 40.5; Opened: 39.5
FPI favorite: Titans by 3.5, 58.8% to win outright
Miami Dolphins -6.5 vs. Cleveland Browns
Sunday, 4:05 p.m., CBS
Money Line: Dolphins (-300) ; Browns (+250)
Total: 40.5; Opened: 40.5
FPI favorite: Dolphins by 1.7, 54.8% to win outright
Green Bay Packers vs. Minnesota Vikings -1.5
Sunday, 4:25 p.m., FOX
Money Line: Packers (+100) ; Vikings (-120)
Total: 48.5; Opened: 48.5
FPI favorite: Packers by 2.1, 55.3% to win outright
Atlanta Falcons vs. Washington Commanders -4
Sunday, 8:20 p.m., NBC, Peacock
Money Line: Falcons (+170) ; Commanders (-200)
Total: 47.5; Opened: 47.5
FPI favorite: Commanders by 3.8, 60.3% to win outright
Detroit Lions -3.5 vs. San Francisco 49ers
Monday, 8:15 p.m., ESPN, ABC
Money Line: Lions (-190) ; 49ers (+160)
Total: 51.5; Opened: 51.5
FPI favorite: Lions by 4.5, 61% to win outright