Alejandro Garnacho was not been included in Manchester United's squad for the team's final match of the Premier League season against Aston Villa, while head coach Ruben Amorim sought to reassure fans that club captain Bruno Fernandes will not be leaving the club this summer.
Sources have told ESPN that Garnacho is increasingly likely to leave United this summer after he was named on the bench for Wednesday's Europa League final.
United and Garnacho's representatives are expected to have a meeting in the coming days to discuss the Argentina international's exit during the summer transfer window.
"Garnacho is a Man United player that is not in the squad today and I have no news that will change today," Amorim told reporters after Man United's 2-0 win.
"Garnacho is one more player of Man United. I don't know what is going to happen in the future," he added."
Speaking ahead of kick-off, Amorim sought to dispel any notion that Fernandes might leave the club after the player appeared to cast doubt over his future following the damaging midweek defeat to Spurs.
"It is important for Bruno to see that we are changing a lot of things in our club," Amorim told TNT Sports.
"The behaviour, the everyday organisation, the pace of training. All these things, if he sees that we are doing that across all levels, he will want to stay at this club. He loves this club.
"That is the most important thing, not the Champions League. He wants to win with this club and he trains and behaves at a high level. Everybody here needs to do that -- he will be here for that."
André Onana was also not present in Amorim's United squad for the match at Old Trafford, though Amorim said the decision was made to give experience to backup Altay Bayindir
"Onana was just for Altay to have this experience and sometimes the goalkeepers need space to play to feel important because we need two or three ready to play," he said.
Goals from Amad Diallo and Christian Eriksen helped United beat 10-man Villa as Amorim's side finished 15th.
Information from ESPN's Rob Dawson and Mark Ogden contributed to this report.