Barcelona coach Hansi Flick has revealed defender Andreas Christensen has picked up another injury just three days after being cleared to return to action against Real Sociedad this weekend.
Christensen, 28, came off the bench against Valencia in Barça's first game of the season in August but was then sidelined until January with Achilles problem.
Upon his return to training at the start of the year, the Denmark international injured his calf, ruling him out until the end of February.
Earlier this week, Barça confirmed Christensen had been given the green light to play competitively again, but he received another setback on Saturday.
"What I can say now is that Andreas got injured in this morning's training session," Flick told a news conference.
"He was an option for Real Sociedad on Sunday, but again he is injured. We are looking now how heavy is the injury. Hopefully it's not so much."
Christensen joined Barça on a free transfer from Chelsea in 2022 and made 32 appearances to help the club win LaLiga in his first season.
He followed his debut campaign up with another 42 appearances last term, being used as a defensive midfielder at times by previous coach Xavi Hernández, but he has been limited to just one outing this season.
In his absence, Pau Cubarsí and Iñigo Martínez have emerged as Barça's first choice centre-back pairing, with Ronald Araújo and Eric García providing backup.
"We want at least four players for this position," Flick added. "Normally we have five really good centre-backs, but without Andreas, it's four.
"Ronald also had a huge injury but he's doing really good now. He's a leader. He has everything to reach a very high level. I am really happy with all of them."
Squad depth may be needed in the coming weeks as the games come thick and fast for the LaLiga leaders.
After Tuesday's 4-4 draw against Atlético Madrid in the first leg of the Copa del Rey semifinal, Barça welcome Real Sociedad in LaLiga this weekend before travelling to Benfica in the Champions League on Wednesday.
Flick aid the fact his side are still in the running to win all three competitions, after already winning the Spanish Supercopa in January, is proof they are exceeding expectations this season.
"We have to accept [the busy schedule] and manage it with the players, maybe by using some fresh legs," he said.
"It's good to have [the games]. We have three competitions and can fight for three titles. When we start this season, at this time now, March 1, no one expected that. The team is going great."