Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Leganés v Rayo Vallecano
Butarque, Leganés, Madrid
Friday, 8 p.m. GMT / 3 p.m. ET
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
LB Juan Cruz | CB Sergio González | CB Matija Nastasic | CB Valentin Rosier | RB Adrià Altimira
DM Yvan Neyou
CM Darko Brasanac | CM Seydouba Cissé
ST Miguel De la Fuente | ST Raba
Injury/suspension updates:
Enric Franquesa, D, knee, OUT, estimated return Sep. 1
Renato Tapia, M, undisclosed, DOUBT
Latest Rayo Vallecano team news
Expected Lineup:
GK Augusto Batalla
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
DM Pathé Ciss | DM Unai López
LW Adri Embarba | AM Isi Palazón | RW Jorge de Frutos
ST Randy Nteka
Injury/suspension updates:
Raul de Tomás, F, illness, OUT, estimated return Feb. 7
Getafe v Sevilla
Estadio Coliseum, Getafe
Saturday, 1 p.m. GMT / 8 a.m. ET
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Juan Berrocal | CB Domingos Duarte | RB Juan Iglesias
CM Luis Milla | CM Djené
LW Coba Da Costa | AM Christantus Uche | RW Carles Pérez
ST Bertug Yildirim
Injury/suspension updates:
Omar Alderete, D, suspension, due back Feb. 9
Mauro Arambarri, M, undisclosed, DOUBT
Luis Milla, M, undisclosed, DOUBT
Allan Nyom, M/D, undisclosed, DOUBT
Latest Sevilla team news
Expected Lineup:
GK Ørjan Nyland
LB Adrià Pedrosa | CB Loïc Badé | CB Nemanja Gudelj | RB José Ángel Carmona
CM Albert Sambi Lokonga | CM Saúl Ñíguez | CM Djibril Sow
FWL Ruben Vargas | ST Isaac Romero | FWR Dodi Lukebakio
Injury/suspension updates:
Valentín Barco, D, groin, DOUBT
Tanguy Nianzou, D, thigh, OUT, estimated return Apr. 13
Villarreal v Real Valladolid
Estadio de la Cerámica, Villarreal
Saturday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Villarreal team news
Expected Lineup:
GK Luiz Júnior
LB Sergi Cardona | CB Logan Costa | CB Juan Foyth | RB
LM Álex Baena | CM Pape Gueye | CM Dani Parejo | RM Yeremy Pino
ST Thierno Barry | ST Gerard Moreno
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Dani Parejo, M, toe, DOUBT
Alfonso Pedraza, D, ankle, OUT, estimated return Feb. 8
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB Lucas Rosa | CB Javi Sánchez | CB David Torres | RB Luis Pérez
LM Anuar | CM Selim Amallah | CM Stanko Juric | RM Iván Sánchez
ST Marcos André | ST Mamadou Diallo
Injury/suspension updates:
Eray Cömert, M/D, hamstring, OUT, estimated return Feb. 23
Mario Martín, M, suspension, due back Feb. 7
Raúl Moro, F/M, collarbone, OUT, estimated return Apr. 6
Atlético Madrid v Mallorca
Riyadh Air Metropolitano, Madrid
Saturday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB Samuel Lino | CB José María Giménez | CB Robin Le Normand | CB Clément Lenglet | RB Nahuel Molina
CM Pablo Barrios | CM Koke | CM Marcos Llorente
ST Julián Álvarez | ST Antoine Griezmann
Injury/suspension updates:
Rodrigo De Paul, M, suspension, due back Feb. 8
Javi Galán, D, ankle, OUT, estimated return Feb. 8
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Mateu Morey
DM Samú Costa | DM Antonio Sánchez
LW Cyle Larin | AM Sergi Darder | RW Dani Rodríguez
ST Vedat Muriqi
Injury/suspension updates:
Valery Fernández, M, undisclosed, DOUBT
Pablo Maffeo, D, undisclosed, OUT, estimated return Feb. 10
Omar Mascarell, M, suspension, due back Feb. 10
Manu Morlanes, M, knee, OUT, estimated return Sep. 1
Antonio Sánchez, M, hamstring, DOUBT
Espanyol v Real Madrid
RCDE Stadium, Barcelona
Saturday, 8 p.m. GMT / 3 p.m. ET
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Brian Oliván | CB Leandro Cabrera | CB Marash Kumbulla | RB Omar El Hilali
DM Alex Král
LM Javier Puado | CM Álvaro Tejero | CM Pol Lozano | RM Jofre Carreras
ST Roberto Fernández
Injury/suspension updates:
José Gragera, M, illness, DOUBT
Brian Oliván, D, undisclosed, DOUBT
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Fran García | CB Antonio Rüdiger | CB Aurélien Tchouaméni | RB Lucas Vázquez
DM Federico Valverde | DM Dani Ceballos
LW Vinícius Jr. | AM Jude Bellingham | RW Rodrygo
ST Kylian Mbappé
Injury/suspension updates:
Eduardo Camavinga, M, hamstring, DOUBT
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Éder Militão, D, knee, OUT, estimated return Aug. 1
Barcelona v Alavés
Estadi Olímpic Lluís Companys, Barcelona
Sunday, 1 p.m. GMT / 8 a.m. ET
Latest Barcelona team news
Expected Lineup:
GK Wojciech Szczesny
LB Alejandro Balde | CB Ronald Araújo | CB Pau Cubarsí | RB Jules Koundé
DM Marc Casadó | DM Frenkie de Jong
LW Raphinha | AM Gavi | RW Lamine Yamal
ST Ferran Torres
Injury/suspension updates:
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Andreas Christensen, D, calf, OUT, estimated return Feb. 17
Iñigo Martínez, D, hamstring, OUT, estimated return Feb. 16
Dani Olmo, F/M, calf, DOUBT
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Latest Alavés team news
Expected Lineup:
GK Jesús Owono
LB Manu Sánchez | CB Moussa Diarra | CB Santiago Mouriño | RB Nahuel Tenaglia
DM Antonio Blanco | DM Ander Guevara
LW Tomás Conechny | AM Jon Guridi | RW Carlos Vicente
ST Enrique García
Injury/suspension updates:
Abdel Abqar, D, suspension, due back Feb. 9
Joan Jordán, M, undisclosed, OUT, estimated return Feb. 2
Antonio Sivera, G, hand, OUT, estimated return Feb. 16
Valencia v Celta Vigo
Mestalla, Valencia
Sunday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Valencia team news
Expected Lineup:
GK Giorgi Mamardashvili
LB José Gayà | CB Yarek Gasiorowski | CB Cristhian Mosquera | RB Dimitri Foulquier
LM Luis Rioja | CM Pepelu | CM Javi Guerra | RM Diego López
ST Hugo Duro | ST André Almeida
Injury/suspension updates:
Enzo Barrenechea, M, undisclosed, DOUBT
Thierry Correia, D, knee, OUT, estimated return Jul. 1
Rafa Mir, F, quadriceps, DOUBT
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
CB Carlos Domínguez | CB Yoel Lago | CB Javi Rodríguez
LM Mihailo Ristic | CM Fran Beltrán | CM Hugo Sotelo | RM Sergio Carreira
AM Pablo Durán | AM Williot Swedberg
ST Borja Iglesias
Injury/suspension updates:
Marcos Alonso, M/D, suspension, due back Feb. 8
Hugo Álvarez, M, suspension, due back Feb. 8
Iago Aspas, F, calf, OUT, estimated return Feb. 9
Óscar Mingueza, D, suspension, due back Feb. 2
Osasuna v Real Sociedad
El Sadar, Pamplona
Sunday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Osasuna team news
Expected Lineup:
GK Sergio Herrera
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
DM Lucas Torró
LM Enrique Barja | CM Jon Moncayola | CM Aimar Oroz | RM Rubén García
ST Ante Budimir
Injury/suspension updates:
Moi Gómez, F/M, illness, DOUBT
Bryan Zaragoza, M, foot, DOUBT
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Javi López | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
DM Martín Zubimendi
LM Sergio Gómez | CM Brais Méndez | CM Luka Sucic | RM Takefusa Kubo
ST Mikel Oyarzabal
Injury/suspension updates:
Hamari Traoré, D, knee, OUT, estimated return May. 4
Real Betis v Athletic Club
Benito Villamarín, Sevilla
Sunday, 8 p.m. GMT / 3 p.m. ET
Latest Real Betis team news
Expected Lineup:
GK Adrián
LB Romain Perraud | CB Natan | CB Diego Llorente | RB Marc Bartra
DM Johnny Cardoso | DM Marc Roca
LW Abde Ezzalzouli | AM Isco | RW Jesús Rodriguez
ST Vitor Roque
Injury/suspension updates:
Chimy Ávila, F, knee, DOUBT
Marc Bartra, D, undisclosed, DOUBT
Héctor Bellerín, D, foot, DOUBT
Jesús Rodriguez, F/M, undisclosed, DOUBT
William Carvalho, M, achilles, OUT, estimated return May. 4
Giovani Lo Celso, F/M, groin, DOUBT
Ricardo Rodríguez, M/D, leg, OUT, estimated return Feb. 8
Aitor Ruibal, D, ankle, DOUBT
Youssouf Sabaly, D, hamstring, OUT, estimated return Feb. 16
Latest Athletic Club team news
Expected Lineup:
GK Unai Simón
LB Adama Boiro | CB Yeray | CB Dani Vivian | RB Andoni Gorosabel
DM Mikel Jauregizar | DM Mikel Vesga
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Gorka Guruzeta
Injury/suspension updates:
Iñigo Ruiz de Galarreta, M, hamstring, OUT, estimated return Feb. 8
Nico Serrano, F/M, illness, OUT, estimated return Feb. 8
Girona v Las Palmas
Municipal de Montilivi, Girona
Monday, 8 p.m. GMT / 3 p.m. ET
Latest Girona team news
Expected Lineup:
GK Pau López
LB Arnau Martínez | CB David López | CB Juanpe | RB Alejandro Francés
DM Yangel Herrera | DM Iván Martín
LW Bryan Gil | AM Donny van de Beek | RW Viktor Tsygankov
ST Arnaut Danjuma
Injury/suspension updates:
Daley Blind, D, undisclosed, OUT, estimated return Feb. 3
Paulo Gazzaniga, G, undisclosed, OUT, estimated return Feb. 3
Miguel Gutiérrez, M/D, ankle, OUT, estimated return Feb. 3
Ladislav Krejcí, D, groin, OUT, estimated return Feb. 3
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Mika Mármol | CB Scott McKenna | CB Andy Pelmard | RB Álex Suárez
DM Javi Muñoz | DM Kirian Rodríguez
LW Adnan Januzaj | AM Alberto Moleiro | RW Sandro
ST Fábio Silva
Injury/suspension updates:
Marvin, M/D, undisclosed, OUT, estimated return Feb. 16
José Campaña, M, undisclosed, OUT, estimated return Feb. 23
Dário Essugo, M, suspension, due back Feb. 8
Viti, M/D, knee, OUT, estimated return Feb. 8