Week 8 started off with Justin Herbert leading the Los Angeles Chargers in a commanding win over the Minnesota Vikings (37-10).
Sunday's early window closed with a loss for the New York Giants against the Philadelphia Eagles and a devastating leg injury to rookie Cam Skattebo, while the Baltimore Ravens defeated the Chicago Bears bringing their record to 2-5.
The Buffalo Bills brought down the Carolina Panthers 40-9 and the New York Jets came back to win over the Cincinnati Bengals to get their first win of the season.
Here were the highlights, analysis and key moments from Sunday's games: