49ers aim to revive ground game against Jaguars

— The formula for success on offense for the San Francisco 49ers has been pretty consistent since Kyle Shanahan took over as coach in 2017.
Sep 25, 2025, 05:40 pm - AP
Game Odds
2025-09-28T20:05ZOpenSpreadTotalML
Jacksonville JaguarsJaguarsJAX
(2-1)
(2-1, 0-1 Away)
o45.5
-115
+3.5
-115
o47.5
EVEN
+155
San Francisco 49ers49ersSF
(3-0)
(3-0, 1-0 Home)
-4.5
EVEN
-3.5
-105
u47.5
-120
-185

Season Leaders

Jaguars49ers
Trevor Lawrence
671
T. LawrenceQB
63/113, 4 TD, 4 INT
671
Passing Yards
Mac Jones
563
M. JonesQBQ
53/80, 4 TD, 1 INT
563
Travis Etienne Jr.
270
T. Etienne Jr.RB
46 CAR, 1 TD
270
Rushing Yards
Christian McCaffrey
176
C. McCaffreyRB
52 CAR
176
Brenton Strange
137
B. StrangeTE
13 REC
137
Receiving Yards
Ricky Pearsall
281
R. PearsallWRQ
16 REC
281
Travon Walker
2
T. WalkerDE
2
Sacks
Bryce Huff
2
B. HuffDE
2
Foyesade Oluokun
23
F. OluokunLB
23
Tackles
Fred Warner
30
F. WarnerLB
30

Injury Report

Jacksonville Jaguars
NameStatusEst. Return
Bhayshul TutenB. TutenRB
QuestionableShoulder
Sep 28
Dyami BrownD. BrownWR
QuestionableShoulder
Sep 28
Patrick MekariP. MekariG
QuestionableElbow
Sep 28
Ezra ClevelandE. ClevelandG
QuestionableAnkle
Sep 28
Wyatt MilumW. MilumG
QuestionableKnee
Sep 28
San Francisco 49ers
NameStatusEst. Return
Ricky PearsallR. PearsallWR
QuestionableKnee
Sep 28
Mac JonesM. JonesQB
QuestionableKnee - PCL
Sep 28
Brock PurdyB. PurdyQB
QuestionableToe
Sep 28
Jauan JenningsJ. JenningsWR
QuestionableAnkle
Sep 28
Nick BosaN. BosaDE
IRKnee - ACL
Feb 9

LAST FIVE GAMES

Jaguars
DATEOPPRESULT
9/21/25vsHOUW17-10
9/14/25@CINL31-27
9/7/25vsCARW26-10
8/23/25@MIAL14-6
8/17/25@NOT17-17
49ers
DATEOPPRESULT
9/21/25vsARIW16-15
9/14/25@NOW26-21
9/7/25@SEAW17-13
8/23/25vsLACW30-23
8/16/25@LVW22-19
Data is currently unavailable.