Game Odds
Odds by
Matchup Predictor
39.8
%
59.9
%
According to ESPN Analytics
Game Information
Levi's Stadium
4:05 PM, September 28, 2025Coverage: FOX
Santa Clara, CA
Injury Report
Jacksonville Jaguars| Name, Pos | Status | Est. Return Date |
|---|---|---|
| CB | IR | Feb 9 |
| TE | QUESTIONABLE | Aug 17 |
| DE | QUESTIONABLE | Aug 17 |
| LB | QUESTIONABLE | Aug 17 |
| OT | QUESTIONABLE | Sep 7 |
San Francisco 49ers| Name, Pos | Status | Est. Return Date |
|---|---|---|
| CB | QUESTIONABLE | Aug 16 |
| RB | IR | Feb 9 |
| WR | QUESTIONABLE | Sep 7 |
| WR | PUP-P | Sep 7 |
| CB | QUESTIONABLE | Aug 16 |
Data is currently unavailable.
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2025 AFC South Standings
| Team | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Jacksonville | 0 | 1 | 0 | .000 | 25 | 31 |
| Indianapolis | 0 | 1 | 0 | .000 | 16 | 24 |
| Houston | 0 | 1 | 0 | .000 | 10 | 20 |
| Tennessee | 0 | 1 | 0 | .000 | 7 | 29 |
2025 NFC West Standings
| Team | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Los Angeles | 1 | 0 | 0 | 1.000 | 31 | 21 |
| Arizona | 1 | 0 | 0 | 1.000 | 20 | 17 |
| Seattle | 0 | 0 | 1 | .500 | 23 | 23 |
| San Francisco | 0 | 1 | 0 | .000 | 9 | 30 |
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