The Chicago Cubs placed left-hander Jordan Wicks on the 15-day injured list on Sunday with a strained forearm.
The 27-year-old Wicks was scheduled to start the series finale at Boston, but he was scratched on Saturday.
"There was a forearm issue and I think it made sense for us to be cautious here," Chicago manager Craig Counsell said. "We'll see how it responds over the next week and see where we're at. The hope is maybe we caught this soon enough and it's a short stay."
Wicks is 1-2 with a 5.70 ERA in five starts.
The Cubs also optioned lefty Luke Little to Triple-A Iowa before the matchup with the Red Sox. Right-hander Daniel Palencia and left-hander Richard Lovelady were brought up from the team's top minor league affiliate.
Palencia has made three appearances with Chicago this season, working six innings and giving up four earned runs.
The 23-year-old Little has a 7.00 ERA over 10 appearances for the Cubs this year. He gave up five runs while recording only two outs in relief during Saturday's 17-0 loss to the Red Sox.