The NFL's Week 7 slate wraps up with a pair of "Monday Night Football" games. The Tampa Bay Buccaneers visit the Detroit Lions (-5.5, 52.5) to get things started (7 p.m. ET on ABC), and the Seattle Seahawks (-3.5, 41.5) host the Houston Texans to close out the week (10 p.m. ET on ESPN).
Matt Bowen, Liz Loza, Pamela Maldonado and Seth Walder offer their picks, prop plays and analysis to help you bet the games.
Note: Odds at time of publication. For the latest updates, visit ESPN BET Sportsbook.
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TB-DET: Game picks
Prop bets | Betting trends
HOU-SEA: Game picks
Prop bets | Betting trends
The Buccaneers defeated the San Francisco 49ers 30-19 last week -- their only victory by more than three points -- to move to 5-1. Led by Baker Mayfield, the Buccaneers are -500 favorites to win the NFC South.
The Detroit Lions dropped to 5-2 after suffering a 30-17 loss to the Kansas City Chiefs last week, but at +750 are tied for the third choice to win the Super Bowl, trailing only the Chiefs (+500) and Buffalo Bills (+650).
Monday night's game has the second-highest total of the week (52.5), behind only Sunday's Washington Commanders-Dallas Cowboys matchup that closed at 54.5.
Buccaneers-Lions game bets
Notable player props, bets
J.J. Watt joins "The Pat McAfee Show" to break down what Baker Mayfield has brought to the Buccaneers this season.
David Montgomery to go UNDER 44.5 rushing yards (-120)
Loza: Montgomery has averaged 33.6 rushing yards per game over his past three contests. He struggled mightily versus the Browns' top-ranked run defense, posting 12 rushing yards on nine totes in Week 4. Tampa Bay's run-stopping operation is on par with Cleveland's, having allowed just 3.7 YPC to rushers (fifth fewest) and an average of 65.3 rushing yards per game to opposing RBs. Although the game script is expected to lean Monty's way, his time-share with Jahmyr Gibbs (who has recorded 22 more carries on the season) poses an additional obstacle. Between the RB-by-committee and the stiff matchup, Montgomery could struggle to clear even 40 rushing yards.
Mike Evans to score Anytime TD (+120)
Bowen: With Evans (hamstring) expected to return, look for Baker Mayfield to target his No. 1 receiver in the low red zone (slant or fade). And Evans gets to match up versus a Lions defense that has allowed 12 touchdown throws this season.
Sam LaPorta to record 5+ receptions (Even), score Anytime TD (+160)
Maldonado: LaPorta's connection with Jared Goff has been rock solid, and this matchup sets up the tight end for another productive night. LaPorta has averaged just over five targets per game and has scored in back-to-back weeks. With Detroit expected to lean on play-action against Tampa's aggressive front, LaPorta's role as a safety valve and red zone option should stay steady. The Bucs have struggled to contain tight ends, giving them plenty of space to operate. Five catches and a touchdown is right in line with how this offense moves when it's clicking.
Betting trends
Courtesy ESPN Research
The Buccaneers are 16-4 ATS on the road since acquiring Baker Mayfield before the 2023 season, the best record in the NFL in that span (3-0 ATS this season).
Four straight Buccaneers games have gone over the total.
Detroit is 3-0 ATS as a favorite this season and has covered 11 straight games following a loss, the longest streak since the 2018-22 Packers (12).
The Lions are 14-4 ATS with extra rest under Dan Campbell.
The Seahawks are coming off a 20-12 victory at Jacksonville and are part of a cluster of teams at 4-2 in the NFC West, joining the San Francisco 49ers and Los Angeles Rams.
Meanwhile, Houston has won two in a row after dropping its first three games of the season. The Texans have won the AFC South the past two years, but they are now the third choice at +800, trailing the Indianapolis Colts (-250) and Jacksonville Jaguars (+300).
Texans-Seahawks game bets
Total points UNDER 41.5 (-120)
Maldonado: Both defenses are too disciplined and efficient to expect a shootout. Seattle is top five in points allowed per drive, while Houston leads the league and has held every opponent below 21 points. The Seahawks' offense leans on chunk plays that are tough to sustain against a pressure-heavy front. Both teams are conservative in pace and red zone attack, trading field goals instead of touchdowns. With Houston's run defense forcing Seattle to the air and C.J. Stroud facing constant pressure, this projects as a slow, physical battle.
Notable player props, bets
Sam Darnold to go OVER 224.5 passing yards (-115)
Bowen: I don't love the pass game matchup for Darnold versus the Houston defense, but he has thrown for over 242 yards in five of six games played this season. With Jaxon Smith-Njigba's ability to uncover, Darnold has a volume target to distribute the ball to, and the Seahawks will scheme their shot plays against Houston's zone looks.
C.J. Stroud to go OVER 20.5 passing completions (-130)
Loza: Stroud has registered 22 or more completions in each of his past three outings. The Seahawks' defensive front has been dominant, notching 20 sacks (third most) thus far in 2025. Although Seattle's defense figures to take advantage of the Texans' flimsy offensive line, the extra week of rest should help Houston and, by extension, Stroud. Given the team's subpar run game, Stroud will have to put the ball in the air. The Seahawks have allowed an average of 26 completions per game.
Tory Horton to record 50+ receiving yards (+500)
Walder: Horton is exactly the type of receiver we want to target for an upside play like this. He runs deep fades and go routes 21% of the time, which (entering Week 7) ranked third-highest among wide receivers with at least 80 routes run and a 53% vertical route rate (fourth). All those deep routes make him more likely to hit 50 yards in a game than the average wideout whose regular receiving yard prop line is 18.5 -- as is the case for Horton on Monday. Plus, the fifth-round rookie has shown some ability; he's averaging 2.2 yards per route run versus man coverage so far this season.
Betting trends
Courtesy ESPN Research
Houston is 0-3 ATS versus teams with winning records in 2025 and 1-4 ATS in its past five as an underdog.
The Seahawks are 3-9 ATS in home games under Mike Macdonald.
Unders are 26-13 in Texans games under DeMeco Ryans, the highest rate in the NFL in that span. Unders are 4-1 in Texans games this season.