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College football betting lines: Ranked USF looks to upset another in-state rival

Keshaun Singleton of the USF Bulls catches a touchdown pass on Saturday. James Gilbert/Getty Images

Fresh off of their upset win over then-No. 13 Florida, the South Florida Bulls enter the top 25 rankings at No. 18, their first appearance in the AP Top 25 since 2018. The Bulls beat then-No. 25 Boise State in Week 1, and will look for their third ranked win in a row as they face No. 6 Miami.

Despite the Gators falling out of the top 25, the SEC had 11 teams ranked this week, the most that any conference has ever had in a week, according to ESPN Research. SEC teams will take part in two ranked matchups this week, as No. 6 Georgia heads to Rocky Top to take on No. 15 Tennessee, and No. 16 Texas A&M play in prime time against No. 8 Notre Dame.

All times Eastern. For latest lines, go to ESPN BET

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Indiana State at No. 22 Indiana
Friday, 6:30 p.m., BTN

Records: Indiana State 2-0 (1st in MVFC); Indiana 2-0, 0-0 vs. AP teams

No line posted

FPI Projection Indiana by 46.5 points, >99% probability to win game


No. 4 Oregon -27.5 at Northwestern
Saturday, Noon, FOX

Records: Oregon 2-0, 0-0 vs. AP teams; Northwestern 1-1, 0-0 vs. AP teams
Opening Line: Oregon -27.5, O/U 51.5
Money line: Oregon (-6000); Northwestern (+1800)
Over/Under: 51.5 (O EVEN, U 120)

FPI Projection Oregon by 23.1 points, 95% probability to win game


No. 12 Clemson -9.5 at Georgia Tech
Saturday, Noon, ESPN

Records: Clemson 1-1, 0-1 vs. AP teams; Georgia Tech 2-0, 0-0 vs. AP teams
Opening Line: Clemson -9.5, O/U 58.5
Money line: Clemson (-300); Georgia Tech (+250)
Over/Under: 58.5 (O -110, U 110)

FPI Projection Georgia Tech by 1.3 points, 56% probability to win game


No. 13 Oklahoma -24.5 at Temple
Saturday, Noon, ESPN2

Records: Oklahoma 2-0, 1-0 vs. AP teams; Temple 2-0, 0-0 vs. AP teams
Opening Line: Oklahoma -24.5, O/U 51.5
Money line: Oklahoma (-4000); Temple (+1300)
Over/Under: 51.5 (O EVEN, U 120)

FPI Projection Oklahoma by 12.1 points, 85% probability to win game


Wisconsin at No. 19 Alabama -20.5
Saturday, Noon, ABC

Records: Wisconsin 2-0, 0-0 vs. AP teams; Alabama 1-1, 0-0 vs. AP teams
Opening Line: Alabama -20.5, O/U 47.5
Money line: Wisconsin (+900); Alabama (-1800)
Over/Under: 47.5 (O -105, U -115)

FPI Projection Alabama by 15.7 points, 89% probability to win game


Central Michigan at No. 23 Michigan -27.5
Saturday, Noon, BTN

Records: Central Michigan 1-1, 0-0 vs. AP teams; Michigan 1-1, 0-1 vs. AP teams
Opening Line: Michigan -27.5, O/U 42.5
Money line: Off
Over/Under: 42.5 (O EVEN, U -120)

FPI Projection Michigan by 24.7 points, 95% probability to win game


South Alabama at No. 24 Auburn -24.5
Saturday, 12:45 p.m., SEC Network

Records: South Alabama 1-1, 0-0 vs. AP teams; Auburn 2-0, 0-0 vs. AP teams
Opening Line: Auburn -24.5, O/U 53.5
Money line: South Alabama (+1300); Auburn (-4000)
Over/Under: 53.5 (O -110, U -110)

FPI Projection Auburn by 20.9 points, 93% probability to win game


Villanova at No. 2 Penn State
Saturday, 3:30 p.m., FS1

Records: Villanova 1-0 (3rd in CAA); Penn State 2-0, 0-0 vs. AP teams

No line posted

FPI Projection Penn State by 45.3 points, >99% probability to win game


No. 6 Georgia -3.5 at No. 15 Tennessee
Saturday, 3:30 p.m., ABC

Records: Georgia 2-0, 0-0 vs. AP teams; Tennessee 2-0, 0-0 vs. AP teams
Opening Line: Georgia -3.5, O/U 50.5
Money line: Georgia (-290); Tennessee (+240)
Over/Under: 50.5 (O -110, U -110)

FPI Projection Tennessee by 0.3 points, 52% probability to win game


Oregon State at No. 21 Texas Tech -23.5
Saturday, 3:30 p.m., FOX

Records: Oregon State 0-2, 0-0 vs. AP teams; Texas Tech 2-0, 0-0 vs. AP teams
Opening Line: Texas Tech -23.5, O/U 61.5
Money line: Oregon State (+1100); Texas Tech (-2500)
Over/Under: 61.5 (O -105, U -115)

FPI Projection Texas Tech by 21.3 points, 94% probability to win game


No. 14 Iowa State -20.5 at Arkansas State
Saturday, 4 p.m., ESPN2

Records: Iowa State 3-0, 1-0 vs. AP teams; Arkansas State 1-1, 0-0 vs. AP teams
Opening Line: Iowa State -20.5, O/U 55.5
Money line: Iowa State (-1800); Arkansas State (+900)
Over/Under: 55.5 (O -110, U -110)

FPI Projection Iowa State by 16 points, 89% probability to win game


Louisiana at No. 25 Missouri -27.5
Saturday, 4 p.m., ESPN+, SECN+

Records: Louisiana 1-1, 0-0 vs. AP teams; Missouri 2-0, 0-0 vs. AP teams
Opening Line: Missouri -27.5, O/U 49.5
Money line: Off
Over/Under: 49.5 (O -110, U -110)

FPI Projection Missouri by 23.6 points, 95% probability to win game


UTEP at No. 7 Texas -41.5
Saturday, 4:15 p.m., SEC Network

Records: UTEP 1-1, 0-1 vs. AP teams; Texas 1-1, 0-1 vs. AP teams
Opening Line: Texas -41.5, O/U 51.5
Money line: Off
Over/Under: 51.5 (O -115, U -105)

FPI Projection Texas by 39.2 points, >99% probability to win game


No. 18 South Florida at No. 5 Miami -17.5
Saturday, 4:30 p.m., The CW Network

Records: South Florida 2-0, 2-0 vs. AP teams; Miami 2-0, 1-0 vs. AP teams
Opening Line: Miami -17.5, O/U 55.5
Money line: South Florida (+500); Miami (-800)
Over/Under: 55.5 (O EVEN, U -120)

FPI Projection Miami by 6.1 points, 72% probability to win game


Ohio at No. 1 Ohio State -32.5
Saturday, 7 p.m., Peacock

Records: Ohio 1-1, 0-0 vs. AP teams; Ohio State 2-0, 1-0 vs. AP teams
Opening Line: Ohio State -32.5, O/U 53.5
Money line: Ohio (+3500); Ohio State (-50000)
Over/Under: 53.5 (O -105, U -115)

FPI Projection Ohio State by 24.4 points, 95% probability to win game


Western Michigan at No. 9 Illinois -27.5
Saturday, 7 p.m., FS1

Records: Western Michigan 0-2, 0-0 vs. AP teams; Illinois 2-0, 0-0 vs. AP teams
Opening Line: Illinois -27.5, O/U 50.5
Money line: Western Michigan (+2000); Illinois (-7500)
Over/Under: 50.5 (O -115, U -105)

FPI Projection Illinois by 25.6 points, 96% probability to win game


Arkansas at No. 17 Ole Miss -9.5
Saturday, 7 p.m., ESPN

Records: Arkansas 2-0, 0-0 vs. AP teams; Ole Miss 2-0, 0-0 vs. AP teams
Opening Line: Ole Miss -9.5, O/U 63.5
Money line: Arkansas (+270); Ole Miss (-340)
Over/Under: 63.5 (O -105, U -115)

FPI Projection Ole Miss by 6.6 points, 74% probability to win game


Florida at No. 3 LSU -9.5
Saturday, 7:30 p.m., ABC

Records: Florida 1-1, 0-0 vs. AP teams; LSU 2-0, 1-0 vs. AP teams
Opening Line: LSU -9.5, O/U 50.5
Money line: Florida (+270); LSU (-340)
Over/Under: 50.5 (O EVEN, U -120)

FPI Projection LSU by 2.8 points, 62% probability to win game


No. 16 Texas A&M at No. 8 Notre Dame -6.5
Saturday, 7:30 p.m., NBC, Peacock

Records: Texas A&M 2-0, 0-0 vs. AP teams; Notre Dame 0-1, 0-1 vs. AP teams
Opening Line: Notre Dame -6.5, O/U 49.5
Money line: Texas A&M (+210); Notre Dame (-250)
Over/Under: 49.5 (O -105, U -115)

FPI Projection Notre Dame by 5.8 points, 71% probability to win game


Vanderbilt at No. 11 South Carolina -5.5
Saturday, 7:45 p.m., SEC Network

Records: Vanderbilt 2-0, 0-0 vs. AP teams; South Carolina 2-0, 0-0 vs. AP teams
Opening Line: South Carolina -5.5, O/U 47.5
Money line: Vanderbilt (+170); South Carolina (-200)
Over/Under: 47.5 (O -110, U -110)

FPI Projection South Carolina by 3.8 points, 65% probability to win game


No. 20 Utah -23.5 at Wyoming
Saturday, 8 p.m., CBSSN

Records: Utah 2-0, 0-0 vs. AP teams; Wyoming 2-0, 0-0 vs. AP teams
Opening Line: Utah -23.5, O/U 48.5
Money line: Utah (-3000); Wyoming (+1200)
Over/Under: 48.5 (O -110, U -110)

FPI Projection Utah by 20 points, 93% probability to win game