The 2025 men's NCAA tournament tips off Thursday and with it comes the excitement of the round of 64 -- one of the most thrilling betting opportunities in all of sports.
Whether you're eyeing point spreads, moneylines or over/unders, certain matchups stand out as prime betting opportunities.
Here is Greg Peterson to factor in team trends, injuries, momentum and more to identify the smartest wagers to make as March Madness gets underway.
Odds are accurate as of publication time. For the latest odds, go to ESPN BET.
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