Arkansas center Frank Ragnow will miss the remainder of the regular season with a high-ankle sprain, coach Bret Bielema said on Monday.
Ragnow, a preseason All-SEC selection, injured the ankle during Saturday's 52-20 loss to Auburn.
Bielema said that the injury will require a "minor procedure" that will come with a 12-week recovery timetable.
By losing Ragnow, Arkansas, which dropped to 2-5 with the loss to Auburn, will have to replace a three-year starter and Outland Trophy Watch List member.
Bielema also announced that freshman running back Chase Hayden will miss the rest of the season with a broken leg.
Arkansas travels to Ole Miss on Saturday.