The 2023 NFL season kicked off Thursday night with Patrick Mahomes and the defending Super Bowl champion Kansas City Chiefs losing to the rising Detroit Lions. 21-20.Fourteen more games are on the slate Sunday, including a prime-time showdown between the Dallas Cowboys and the New York Giants. Monday Night Football (ESPN, ABC and ESPN+) will feature the Super Bowl hopeful Buffalo Bills against Aaron Rodgers' new team, the New York Jets.
Check back here daily for updated lines and information from ESPN Stats & Information.
Lines courtesy of Caesars Sportsbook. Football Power Index (FPI) by ESPN Sports Analytics Group.
Carolina Panthers @ Atlanta Falcons -3.5
Mercedes-Benz Stadium, Atlanta, GA
Sunday 1:00 PM ET
Opening Favorite: Atlanta Falcons -2
Money Line: Carolina Panthers (+158) ; Atlanta Falcons (-190)
Total: 40; Opened: 39.5
FPI favorite: Atlanta Falcons (55.9%)
Betting Nuggets
The Falcons are 1-6 ATS in their last seven Week 1 games. The Panthers are 7-13 ATS in their last 20 Week 1 games.
Unders are 15-5 in the last 20 meetings.
The Panthers were 8-4 ATS as underdogs last season, covering five of their last six games in that role.
Cincinnati Bengals -2 @ Cleveland Browns
Cleveland Browns Stadium, Cleveland, OH
Sunday 1:00 PM ET
Opening Favorite: Cincinnati Bengals -1
Money Line: Cincinnati Bengals (-130) ; Cleveland Browns (+110)
Total: 47.5; Opened: 46.5
FPI favorite: Cincinnati Bengals (59.2)
Betting Nuggets
Divisional home underdogs are 7-0 ATS in Week 1 over the last five years (4-1-2 SU), 15-2-1 ATS since 2012 and 21-5-1 ATS since 2009
The Bengals are 13-4 ATS on the road in the last two seasons. Joe Burrow is 15-7 ATS in his career on the road (12-4 ATS last two seasons).
Unders went 5-1 in Deshaun Watson starts last season.
Jacksonville Jaguars -4.5 @ Indianapolis Colts
Lucas Oil Stadium, Indianapolis, IN
Sunday 1:00 PM ET
Opening Favorite: Jacksonville Jaguars -3
Money Line: Jacksonville Jaguars (-225) ; Indianapolis Colts (+185)
Total: 46; Opened: 43
FPI favorite: Jacksonville Jaguars (64.5)
Betting Nuggets
The Colts are 1-13-1 ATS in their last 15 Week 1 games (0-7-1 ATS last eight).
The Jaguars are 13-2-1 ATS against the Colts since 2015. The Colts had been favored in the previous 10 meetings. This is the third time ever that the Jaguars have been road favorites in Indianapolis (2017, 2011).
Jacksonville is 1-4 ATS as a favorite under Doug Pederson. The Jaguars are 1-7 ATS as favorites since 2020 and 5-14 ATS since 2018.
Tampa Bay Buccaneers @ Minnesota Vikings -5
U.S. Bank Stadium, Minneapolis, MN
Sunday 1:00 PM ET
Opening Favorite: Minnesota Vikings -5
Money Line: Tampa Bay Buccaneers (+192) ; Minnesota Vikings (-235)
Total: 46; Opened: 45.5
FPI favorite: Minnesota Vikings (67.1%)
Betting Nuggets
The Buccaneers were 2-13-1 ATS in their last 16 games last season including playoffs. They were 0-4 ATS as underdogs last season, and they were 0-6 ATS in their final six road games.
Overs were 8-2 in Minnesota home games last season including playoffs (8-1 in last nine). Over the last three seasons, overs are 20-6 in Vikings home games.
Tennessee Titans @ New Orleans Saints -3
Caesars Superdome, New Orleans, LA
Sunday 1:00 PM ET
Opening Favorite: New Orleans Saints -3
Money Line: Tennessee Titans (+130) ; New Orleans Saints (-155)
Total: 41.5; Opened: 41
FPI favorite: New Orleans Saints (53.4%)
Betting Nuggets
The Titans are 23-14-1 ATS as underdogs under Vrabel, including 22-9-1 ATS when getting at least three points.
Dennis Allen is 21-32 ATS in his career (.396).
Out of 168 coaches to coach at least 50 games in the Super Bowl era, Allen is the only one with a cover percentage below 40%.
Tennessee is 1-4 ATS in Week 1 under Mike Vrabel (0-3 ATS last three seasons). The only cover came in the only instance they have been underdogs in Week 1 (2019 at Browns).
San Francisco 49ers -2 @ Pittsburgh Steelers
Acrisure Stadium, Pittsburgh, PA
Sunday 1:00 PM ET
Opening Favorite: San Francisco 49ers -2
Money Line: San Francisco 49ers (-140) ; Pittsburgh Steelers (+118)
Total: 41.5; Opened: 41
FPI favorite: San Francisco 49ers (55.9)
Betting Nuggets
Over the last five seasons, the Steelers are 7-1-2 ATS as home underdogs. Mike Tomlin is 14-5-2 ATS and 13-8 outright as a home underdog, both the best marks since Tomlin became Steelers coach in 2007.
Pittsburgh is 3-0 ATS in its last three Week 1 games. San Francisco is 0-3 ATS in that span.
The 49ers covered seven of their last eight regular-season games last season, including going 4-1 ATS in Brock Purdy starts.
Arizona Cardinals @ Washington Commanders -7
FedExField, Landover, MD
Sunday 1:00 PM ET
Opening Favorite:
Money Line: Arizona Cardinals (+250) ; Washington Commanders (-320)
Total: 38; Opened: 0
FPI favorite: Washington Commanders (73.1%)
Betting Nuggets
Since 1996, coaches making their debuts in Week 1 as at least seven-point underdogs are 0-15 outright and 5-10 ATS.
Ron Rivera is 13-2 outright and 10-5 ATS as at least a seven-point favorite, all with the Panthers.
The Cardinals are 10-3 ATS as road underdogs in the last two seasons. They are 12-5 ATS on the road and 13-7 ATS as underdogs in that span.
Houston Texans @ Baltimore Ravens -9.5
M&T Bank Stadium, Baltimore, MD
Sunday 1:00 PM ET
Opening Favorite: Baltimore Ravens -10
Money Line: Houston Texans (+345) ; Baltimore Ravens (-455)
Total: 43.5; Opened: 43.5
FPI favorite: Baltimore Ravens (73.5%)
Betting Nuggets
The Ravens are 6-1 ATS in their last seven Week 1 games.
The Ravens are 43-0 outright as double-digit favorites in the regular season.
Last season, the Texans were 6-3 ATS as at least seven-point underdogs and 4-1 ATS as double-digit underdogs.
Green Bay Packers @ Chicago Bears -1.5
Soldier Field, Chicago, IL
Sunday 4:25 PM ET
Opening Favorite: Chicago Bears -1
Money Line: Green Bay Packers (+105) ; Chicago Bears (-125)
Total: 41.5; Opened: 41.5
FPI favorite: Chicago Bears (51.5%)
"Betting Nuggets
Matt LaFleur is 8-0 outright and ATS against the Bears. The eight-game cover streak is the longest active intradivision cover streak in the NFL.
Justin Fields is 8-16-1 ATS in his career, the second-worst record among quarterbacks to start at least 25 games in the Super Bowl era (Colt McCoy). He is 4-8-1 ATS at home.
The Bears are 2-10 ATS in division games in the last two seasons.
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Las Vegas Raiders @ Denver Broncos -3.5
Empower Field at Mile High, Denver, CO
Sunday 4:25 PM ET
Opening Favorite:
Money Line: Las Vegas Raiders (+140) ; Denver Broncos (-165)
Total: 43; Opened: 0
FPI favorite: Denver Broncos (59.1%)
Betting Nuggets
The Raiders are 4-0 ATS in the last two seasons against the Broncos.
Sean Payton is 2-6 ATS in his last eight season openers (6-8-1 ATS in career).
Denver's last seven September games have gone under the total. Las Vegas is 0-4 ATS in its last four September games.
Philadelphia Eagles -4 @ New England Patriots
Gillette Stadium, Foxboro, MA
Sunday 4:25 PM ET
Opening Favorite: Philadelphia Eagles -3.5
Money Line: Philadelphia Eagles (-195) ; New England Patriots (+162)
Total: 44.5; Opened: 44.5
FPI favorite: Philadelphia Eagles (61.9)
Betting Nuggets
Since 2000, teams that lost in the previous season's Super Bowl are 4-19 ATS in Week 1 the following season (0-3 ATS last three seasons).
Bill Belichick is 15-8 ATS as a home underdog as Patriots head coach. However, last season, the Patriots were 0-3 ATS as home underdogs.
Five straight Patriots Week 1 games have gone under the total.
Miami Dolphins @ Los Angeles Chargers -3
SoFi Stadium, Inglewood, CA
Sunday 4:25 PM ET
Opening Favorite: Los Angeles Chargers -2.5
Money Line: Miami Dolphins (+140) ; Los Angeles Chargers (-165)
Total: 51; Opened: 48.5
FPI favorite: Los Angeles Chargers (55.4%)
Betting Nuggets
The Chargers are 8-1-2 ATS in their last 11 Week 1 games (three straight covers).
Tua Tagovailoa is 9-5-1 ATS in his career as an underdog.
Los Angeles Rams @ Seattle Seahawks -5
Lumen Field, Seattle, WA
Sunday 4:25 PM ET
Opening Favorite: Seattle Seahawks -4
Money Line: Los Angeles Rams (+185) ; Seattle Seahawks (-225)
Total: 46; Opened: 46
FPI favorite: Seattle Seahawks (62.7%)
Betting Nuggets
Over the last four seasons, the Rams are 8-1 ATS against the Seahawks including playoffs. Overall, Sean McVay is 9-4 ATS against Pete Carroll.
Seattle has won four straight Week 1 games and has covered three straight Week 1 games.
Dallas Cowboys -3.5 @ New York Giants
MetLife Stadium, East Rutherford, NJ
Sunday 8:20 PM ET
Opening Favorite: Dallas Cowboys -2.5
Money Line: Dallas Cowboys (-170) ; New York Giants (+143)
Total: 45; Opened: 45
FPI favorite: Dallas Cowboys (55.3)
Betting Nuggets
The Giants were 13-4 ATS last season (14-5 ATS including playoffs), the best mark in the NFL.
Over the last two seasons, unders are 30-10-1 in prime-time games when the road team is favored.
Divisional home underdogs are 7-0 ATS in Week 1 over the last five years (4-1-2 SU).
Buffalo Bills -2.5 @ New York Jets
MetLife Stadium, East Rutherford, NJ
Monday 8:15 PM ET
Opening Favorite: Buffalo Bills -1
Money Line: Buffalo Bills (-145) ; New York Jets (+122)
Total: 45.5; Opened: 45.5
FPI favorite: Buffalo Bills (57.6)
Betting Nuggets
Aaron Rodgers is 6-1 ATS and 5-1-1 outright as a regular-season home underdog. He is 6-0 ATS and 5-0-1 outright in the last six instances.
Unders in Bills road games went 7-1 last season.