The 2026 MLB season begins on Wednesday, March 25, with the Opening Night game between the New York Yankees and San Francisco Giants. Opening Day arrives on Thursday, March 26, with 22 teams in action. Six teams will wait until Friday, March 27 to begin their baseball battles, including the Colorado Rockies visiting the Miami Marlins and the Atlanta Braves playing an interleague contest at home against Kansas City.

While each team's season might not start at exactly the same time, every team does start with a clean slate. Nobody is in first place. Nobody is in last place. We won't have a truly clear picture of which teams will end up making it to baseball's postseason for several months. Still, that doesn't mean we have no idea how the season might play out.

DraftKings has posted win totals and postseason odds for the upcoming season. In the NL, the Los Angeles Dodgers once again begin as favorites to win the most games (102.5) as well as to take their third consecutive World Series crown (+230). At the other end of the spectrum, the Rockies (54.5 wins) are tied with the Washington Nationals for the biggest longshot (500-1) to end up celebrating with champagne this fall.

Here are all of the odds for the NL teams and our thoughts on some potential wagers.

Note: All odds provided by DraftKings Sportsbook and are accurate as of publication time.

Bets for the NL East

Philadelphia Phillies

2025 record: 96-66
2026 win total: 91.5 (O -110/U -110)
Odds to win: Division (+160), NLCS (+700), World Series (13-1)

UNDER 91.5 wins (-115): I'd consider this one more of a lean than a true play, as I'm projecting 88.8 wins for Philadelphia. That's just under three wins under our line here. It's a slight positive EV play, but the margin for error is low, especially if Philly winds up adding anything before the start of the season. Their off-season has been unspectacular so far, losing out on Bo Bichette and seeing Ranger Suarez depart for Boston. Plus there's the Zack Wheeler "elephant in the room" as pitchers often come back from TOS surgery as a shell of their former self, if they come back at all. The team returns plenty of talent, but there are enough holes and question marks to make 90 wins far from a certainty. -- Carty

New York Mets

2025 record: 83-79
2026 win total: 89.5 (O -120/U Even)
Odds to win: Division (+180), NLCS (+850), World Series (17-1)

OVER 89.5 wins (-115): I feel more confident taking the Mets to make the playoffs, but at -250, let's take the chance that president of baseball operations David Stearns' roster makeover pays even more dividends. A lot has to go right, but the pieces are there, keyed by a pair of former Brewers arms fortifying the pitching. Freddy Peralta is an established frontline starter while Devin Williams should rebound and anchor a revamped bullpen. -- Zola

Miami Marlins

2025 record: 79-83
2026 win total: 73.5 (O -105/U -115)
Odds to win: Division (25-1), NLCS (100-1), World Series (180-1)

OVER 73.5 wins (-105): The Marlins overperformed expectations by about seven wins last season, which is reflected in the O/U being significantly below last season's results. However, the club should be better with an intriguing outfield, healthy starters and Pete Fairbanks sealing the deal. -- Zola

Atlanta Braves

2025 record: 76-86
2026 win total: 88.5 (O -110/U -110)
Odds to win: Division (+210), NLCS (+750), World Series (15-1)

To WIN division (+210): Not much separates the Phillies, Mets and Braves. They all have established stars alongside a bevy of risky talent. One of them is going to win the division and, with it coming down to a three-way coin flip, let's back the best odds. Each team needs their pitching to come through and the Braves have more question marks than both the Phillies and Mets, but that's baked into the odds. -- Zola

Washington Nationals

2025 record: 66-96
2026 win total: 69.5 (O -110/U -110)
Odds to win: Division (90-1), NLCS (300-1), World Series (500-1)

UNDER 69.5 wins (-110): The Nationals will challenge the Rockies for the worst record in the National League. They have some intriguing position players, but the pitching is horrible and they won't have Coors Field as an excuse for the over-inflated staff ERA. -- Zola

Bets for the NL Central

Milwaukee Brewers

2025 record: 97-65
2026 win total: 87.5 (O -110/U -110)
Odds to win: Division (+190), NLCS (13-1), World Series (20-1)

OVER 87.5 wins (-115): Is losing Peralta really worth over 10 wins? Brandon Woodruff returns to anchor the Brewers rotation. He's not the workhorse of prior seasons, but before going down with a lat injury in September, Woodruff was elite. Milwaukee has the reputation of getting the most out of their arms, and Jacob Misiorowski, Logan Henderson and Chad Patrick have all shown they can succeed at the MLB level. The Brewers aren't likely to repeat last season's 97 wins, but all they need is 88 to cash the over. -- Zola

Chicago Cubs

2025 record: 92-70
2026 win total: 89.5 (O -110/U -110)
Odds to win: Division (+150), NLCS (+900), World Series (19-1)

To WIN division (+150): While the Cubs lost Kyle Tucker this winter, they added Alex Bregman, Edward Cabrera, and Tyler Austin (who projects as a well above-average hitter after a tour in Korea) and play in perhaps the weakest division in baseball. This line implies we need just a 40% chance in order for this to break even, and my projection system (THE BAT X) is forecasting a 47% chance of Chicago winning this division, with the Brewers as their primary competition. Milwaukee significantly overperformed last year and has already shown they're not afraid to trade their best players if it will save some money and they're currently projected for 2-3 wins less than the Cubs. -- Carty

Cincinnati Reds

2025 record: 83-79
2026 win total: 82.5 (O -120/U Even)
Odds to win: Division (+350), NLCS (22-1), World Series (40-1)

UNDER 82.5 wins (Even): My projections are not sold on the Reds being an average MLB team, mostly due to question marks in their rotation. Andrew Abbott has been one of the luckiest pitchers in baseball, Nick Lodolo's stuff declined after returning from injury last year and Chase Burns represents a significant injury risk. Throw in a weak bullpen, and this pitching staff nearly cracks the bottom five of projected staffs in baseball. THE BAT X projects 79.4 wins for Cincinnati, even after the addition of Eugenio Suarez. -- Carty

St. Louis Cardinals

2025 record: 78-84
2026 win total: 73.5 (O -Even/U -120)
Odds to win: Division (13-1), NLCS (90-1), World Series (200-1)

UNDER 73.5 wins (-120): A slight correction to an earlier note: the Nationals will challenge the Rockies and Cardinals for the worst record in the NL. Of course, that's baked into this O/U, but the Cardinals' Opening Day starter is slated to be Matthew Liberatore. Enough said. The lineup has some nice parts, but the rotation and bullpen are both in complete rebuilding mode. Liberatore and Michael McGreevy could emerge as quality starters, but overall, this team will be lucky to win 70 games. -- Zola

Pittsburgh Pirates

2025 record: 71-91
2026 win total: 75.5 (O -110/U -110)
Odds to win: Division (12-1), NLCS (65-1), World Series (100-1)

OVER 75.5 wins (-110): That groan you just made? That's the signal that this is a good bet. Nobody wants to bet on bad teams to be good -- or even on bad teams to be less bad. But you have to realize that the market already knows the Pirates are bad, the same as you and I do. We're betting on how bad. Savvy acquisitions like Brandon Lowe and Ryan O'Hearn, paired with high-upside young talent like Konnor Griffin and Bubba Chandler, make this team a sneaky bet to be much better than you'd otherwise think. -- Carty

Bets for the NL West

Los Angeles Dodgers

2025 record: 93-69
2026 win total: 102.5 (O -120/U Even)
Odds to win: Division (-600), NLCS (+130), World Series (+250)

To WIN division (-600): Wait a minute! We're betting on the Dodgers? Has Carty lost his mind? I've spent the last 30 minutes reading about how he only wants to bet overs on bad teams and unders on good teams. This is the Dodgers -- the best team in baseball and everyone knows it! There can't possibly be value on them! Except, somehow, there is. Not on their win total, and not a whole lot on their postseason odds, but their division odds actually give us a chance to exploit a line that is shaded too far because of another "bad bettor" maxim of which books are aware.

Bad bettors often won't bet odds that are too steep, and -600 is steep. The Dodgers would need at least an 85% chance to win the division for this to be a break-even bet. Now read that sentence again, but slower. An 85% chance! For the Dodgers! DraftKings has them winning 17 more games than the second-place team. THE BAT X has them for 20 more wins and projects them for a 96.8% chance to win the division.

Los Angeles has failed to win the division just once in the last 13 years -- and that was in a 107-win season! They haven't finished below 90 wins (which would still put them in line to win this division) since 2008. A whole lot would have to go wrong for this bet to lose and, while we're certainly paying for it, we're not paying enough. Value is value, and -600 is value here disguised as "too much juice." -- Carty

San Diego Padres

2025 record: 90-72
2026 win total: 85.5 (O -105/U -115)
Odds to win: Division (+700), NLCS (13-1), World Series (25-1)

UNDER 85.5 wins (-105): This is a team with more name value than true talent. They overperformed last year and lost more than they gained over the winter. Most notably, the loss of Dylan Cease (and Yu Darvish) gives this rotation at least a couple of holes, and the team may have to rely on their elite bullpen more than they'd like. THE BAT X projects just a 78.9 win total, making this one of the stronger under bets you can make. -- Carty

San Francisco Giants

2025 record: 81-81
2026 win total: 81.5 (O -115/U -105)
Odds to win: Division (15-1), NLCS (30-1), World Series (60-1)

OVER 81.5 wins (-115): The Giants quietly addressed a few needs in the offseason. It wasn't nearly enough to compete with the Dodgers, but they may swap places with the Padres and make a run at the last wild-card spot before falling a couple of games short. Still, adding Harrison Bader and Luis Arraez should help the offense while Adrian Houser and Tyler Mahle add depth to a rotation. Neither are special, but both should benefit from playing in Oracle Park. -- Zola

Arizona Diamondbacks

2025 record: 80-82
2026 win total: 79.5 (O -120/U Even)
Odds to win: Division (16-1), NLCS (30-1), World Series (65-1)

OVER 79.5 wins (-120): The Diamondbacks are going to score. The issue is run prevention. Their rotation and bullpen have been depleted, but based on some of the recent moves to stabilize the offense and defense, the club is likely to address their pitching deficiencies before the season begins. Retaining Ketel Marte, along with adding Carlos Santana and Nolan Arenado, signals that the club isn't ready to write off 2026. -- Zola

Colorado Rockies

2025 record: 43-119
2026 win total: 54.5 (O -115/U -105)
Odds to win: Division (200-1), NLCS (300-1), World Series (500-1)

OVER 54.5 wins (-115): Two seasons ago it was the Athletics. Last season it was the White Sox. This season, it's the Rockies. And by "it", I mean the best bet on the entire board. Nobody wants to bet on teams that were historically bad the previous year. Nobody wants to believe that they could actually be better than the sheer awfulness we've just witnessed. But regression is a thing. The Rockies last year were almost certainly bad and almost certainly had terrible luck on top of it. Look, this is still a bad team -- the worst in baseball. However, THE BAT X is projecting them for 67 wins, which is massively over this reactionary line. -- Carty