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NFL Week 1 betting: Odds, lines and totals for every game

J.J. McCarthy makes his first regular-season start Monday night with the Vikings slight favorites. Brad Rempel/USA TODAY Sports

Week 1 of the NFL season is almost here!

The Philadelphia Eagles begin their Super Bowl title defense Thursday night against the Dallas Cowboys in the NFL's season opener. The Eagles are 7-point favorites against their NFC East rivals, and only one other game this week features a team favored by a touchdown or more (Denver Broncos -8 vs. Tennessee Titans).

A whopping 11 games have spreads of a field goal or less.

Not as surprising, the Sunday night matchup between the Baltimore Ravens and Buffalo Bills has the highest over/under in Week 1, at 52.5 points. Buffalo is a 1.5-point favorite at home in a rematch of last season's AFC divisional round, a game the Bills narrowly won.

The week wraps up with J.J. McCarthy making his regular-season debut when the Minnesota Vikings visit Caleb Williams and the revamped Chicago Bears at Soldier Field on "Monday Night Football" (8:15 ET on ABC/ESPN).

Here's a look at the odds for every Week 1 game.

Odds as of publication time. For the most current odds, visit ESPN BET.

Jump to:
DAL-PHI | KC-LAC | NYG-WAS | TB-ATL
CAR-JAX | MIA-IND | LV-NE | PIT-NYJ
CIN-CLE | ARI-NO | SF-SEA | TEN-DEN
DET-GB | HOU-LAR | BAL-BUF | MIN-CHI

Thursday

Dallas Cowboys at Philadelphia Eagles (-7)
8:20 p.m. ET on NBC, Lincoln Financial Field, Philadelphia

Money line: Eagles -300, Cowboys +250
Total: 46.5 points
FPI favorite: Eagles by 6.7, 66.4% to win outright


Friday

Kansas City Chiefs (-2.5) vs. Los Angeles Chargers
8 p.m. ET on YouTube, Corinthians Arena, São Paulo, Brazil

Money line: Chiefs -155, Chargers +135
Total: 44.5 points
FPI favorite: Chiefs by 3.1, 56.9% to win outright


Sunday

New York Giants at Washington Commanders (-6.5)
1 p.m. ET, Northwest Stadium, Landover, Maryland

Money line: Commanders -400, Giants +300
Total: 45.5 points
FPI favorite: Commanders by 8, 69% to win outright


Tampa Bay Buccaneers (-1.5) at Atlanta Falcons
1 p.m. ET, Mercedes-Benz Stadium, Atlanta

Money line: Buccaneers -135, Falcons +115
Total: 48.5 points
FPI favorite: Buccaneers by 2.3, 55.3% to win outright


Check out the latest odds and lines for every game on ESPN BET.


Carolina Panthers at Jacksonville Jaguars (-2.5)
1 p.m. ET, EverBank Stadium, Jacksonville, Florida

Money line: Jaguars -165, Panthers +140
Total: 45.5 points
FPI favorite: Jaguars by 3.5, 58.9% to win outright


Miami Dolphins at Indianapolis Colts (-1)
1 p.m. ET, Lucas Oil Stadium, Indianapolis

Money line: Dolphins EVEN, Colts -120
Total: 45.5 points
FPI favorite: Colts by 0.2, 49.9% to win outright


Las Vegas Raiders at New England Patriots (-2)
1 p.m. ET, Gillette Stadium, Foxborough, Massachusetts

Money line: Patriots -135, Raiders +115
Total: 43.5 points
FPI favorite: Patriots by 0.8, 51.9% to win outright


Pittsburgh Steelers (-3) at New York Jets
1 p.m. ET, MetLife Stadium, East Rutherford, New Jersey

Money line: Steelers -150, Jets +130
Total: 39.5 points
FPI favorite: Steelers by 3.3, 58.8% to win outright


Cincinnati Bengals (-5.5) at Cleveland Browns
1 p.m. ET, Huntington Bank Field, Cleveland

Money line: Bengals -240, Browns +200
Total: 44.5 points
FPI favorite: Bengals by 6, 65.2% to win outright


Arizona Cardinals (-5.5) at New Orleans Saints
1 p.m. ET, Caesars Superdome, New Orleans

Money line: Cardinals -240, Saints +200
Total: 42.5 points
FPI favorite: Cardinals by 3.1, 57% to win outright


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San Francisco 49ers (-1.5) at Seattle Seahawks
4:05 p.m. ET, Lumen Field, Seattle

Money line: 49ers -125, Seahawks +105
Total: 45.5 points
FPI favorite: 49ers by 1.4, 53.7% to win outright


Tennessee Titans at Denver Broncos (-8)
4:05 p.m. ET, Empower Field at Mile High, Denver

Money line: Broncos -400, Titans +300
Total: 41.5 points
FPI favorite: Broncos by 7.8, 69.8% to win outright


Detroit Lions at Green Bay Packers (-1.5)
4:25 p.m. ET, Lambeau Field, Green Bay, Wisconsin

Money line: Lions +105, Packers -125
Total: 48.5 points
FPI favorite: Lions by 1, 51.9% to win outright


Houston Texans at Los Angeles Rams (-3)
4:25 p.m. ET, Sofi Stadium, Inglewood, California

Money line: Rams -150, Texans +130
Total: 45.5 points
FPI favorite: Rams by 2, 56% to win outright


Baltimore Ravens at Buffalo Bills (-1.5)
8:20 p.m. ET on NBC, Highmark Stadium, Orchard Park, New York

Money line: Bills -125, Ravens +105
Total: 52.5 points
FPI favorite: Bills by 0.8, 52.3% to win outright


Monday

Minnesota Vikings at Chicago Bears (-1)
8:15 p.m. ET on ABC/ESPN, Soldier Field, Chicago

Money line: Bears -110, Vikings -110
Total: 45.5 points
FPI favorite: Bears by 0.9, 52.5% to win outright