MNF: 49ers vs. Colts

The 49ers and Colts round out Week 16 as both teams look to continue their push for the playoffs.

Tonight at 8 p.m. ET

MNF Playbook with Next Gen Stats on ESPN2

Featured

  • SportsCenter

    ESPN • SportsCenter

  • NFL PrimeTime on ESPN+

    ESPN+ • NFL

  • A Tall Tale (Ep. 8)

    ESPN+ • Peyton's Places

  • #9 Alabama vs. #8 Oklahoma (First Round)

    SECN • RE-AIR • NCAA Football

  • Louisville vs. #2 Miami

    ACCN • RE-AIR • NCAA Football

  • Cincinnati vs. Clemson

    ESPNU • RE-AIR • NCAA Men's Basketball

  • USA Dodgeball All-Star Showcase

    ESPNews • RE-AIR • ESPN The Ocho

  • SEC Storied: The Book of Manning

    ESPN2 • RE-AIR • Football

  • SportsCenter

    ESPN Deportes • RE-AIR • ES • SportsCenter Noche

Also Live

  • USA Dodgeball All-Star Showcase

    ESPNews • RE-AIR • ESPN The Ocho

  • SEC Storied: The Book of Manning

    ESPN2 • RE-AIR • Football

  • SportsCenter

    ESPN Deportes • RE-AIR • ES • SportsCenter Noche

Upcoming

See All

  • San Francisco 49ers vs. Indianapolis Colts

    ESPN/ESPN Deportes • EN/ES • NFL

  • MNF Playbook with Next Gen Stats: San Francisco 49ers vs. Indianapolis Colts

    ESPN2 • NFL

  • Washington State vs. Utah State

    ESPN/ESPN Unlimited • EN/ES • NCAA Football

  • Bethune-Cookman vs. #1 Arizona

    ESPN+ • NCAA Men's Basketball

  • North Carolina Central vs. #8 Oklahoma

    SECN+ • NCAA Women's Basketball

  • Eastern Washington vs. #10 BYU

    ESPN+ • NCAA Men's Basketball

  • Davidson vs. #17 Kansas

    ESPN+ • NCAA Men's Basketball

  • Southern Indiana vs. #17 Tennessee

    SECN+ • NCAA Women's Basketball

  • American University vs. #23 Virginia

    ACCN • NCAA Men's Basketball

  • West Georgia vs. #25 Georgia

    SECN+ • NCAA Men's Basketball

  • Temple vs. #25 Princeton

    ESPN+ • NCAA Women's Basketball

  • Athletic Club vs. RCD Espanyol

    ESPN Deportes/ESPN+ • EN/ES • Spanish LALIGA

  • Cleveland Cavaliers vs. New York Knicks

    ESPN/ESPN Unlimited • EN/ES • NBA

  • San Antonio Spurs vs. Oklahoma City Thunder

    ESPN/ESPN Unlimited • EN/ES • NBA

  • Dallas Mavericks vs. Golden State Warriors

    ESPN/ESPN Unlimited • EN/ES • NBA

  • Houston Rockets vs. Los Angeles Lakers

    ESPN/ESPN Unlimited • EN/ES • NBA

  • Minnesota Timberwolves vs. Denver Nuggets

    ESPN/ESPN Unlimited • EN/ES • NBA

  • New York Golf Club vs. Atlanta Drive GC

    ESPN on ABC • TGL

  • Toledo vs. Louisville

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Western Kentucky vs. Southern Miss

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • UNLV vs. Ohio

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • California vs. Hawai'i

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Central Michigan vs. Northwestern

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • New Mexico vs. Minnesota

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Florida International vs. UTSA

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Pittsburgh vs. East Carolina

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Penn State vs. Clemson

    ESPN on ABC • NCAA Football

  • UConn vs. Army

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • #22 Georgia Tech vs. #12 BYU

    ESPN on ABC/ESPN Unlimited • EN/ES • NCAA Football

  • #25 North Texas vs. San Diego State

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • #19 Virginia vs. Missouri

    ESPN on ABC/ESPN Unlimited • EN/ES • NCAA Football

  • LSU vs. #21 Houston

    ESPN/ESPN Deportes • EN/ES • NCAA Football

  • Buffalo Bandits vs. Calgary Roughnecks

    ESPN2/ESPN+ • National Lacrosse League

  • College Football Playoff Bowl

    SECN • NCAA Football

  • Prairie View vs. LSU

    SECN • NCAA Men's Basketball

  • East Carolina vs. #12 North Carolina

    ACCN • NCAA Men's Basketball

  • Stetson vs. Oklahoma

    SECN • NCAA Men's Basketball

  • Providence vs. #3 South Carolina

    SECN • NCAA Women's Basketball

  • Wofford vs. Georgia Tech

    ACCN • NCAA Women's Basketball

  • Stetson vs. Miami

    ACCN • NCAA Women's Basketball

  • SE Louisiana vs. #2 Texas

    SECN • NCAA Women's Basketball

  • Alabama State vs. #5 LSU

    SECN • NCAA Women's Basketball

  • Duke vs. Syracuse

    ACCN • NCAA Women's Basketball

  • NBA Layup Lines

    ESPN Unlimited • NBA

  • NBA Layup Lines

    ESPN Unlimited • NBA

  • NBA Layup Lines

    ESPN Unlimited • NBA

  • Gardner-Webb vs. Wake Forest

    ACCNX • NCAA Women's Basketball

  • South Carolina State vs. South Carolina

    SECN+ • NCAA Men's Basketball

  • Stonehill vs. Syracuse

    ACCNX • NCAA Men's Basketball

  • Jacksonville vs. Florida State

    ACCNX • NCAA Men's Basketball

Recently Added

See All

  • NFL PrimeTime on ESPN+

    ESPN+ • NFL

  • A Tall Tale (Ep. 8)

    ESPN+ • Peyton's Places

  • Sat, 12/20 - #10 Miami vs. #7 Texas A&M (First Round)

    ESPN • NCAA Football

  • Fri, 12/19 - #9 Alabama vs. #8 Oklahoma (First Round)

    ESPN • NCAA Football

  • The Field Is Set (Ep. 1)

    ESPN+ • NCAA Football

  • NFL Turning Point: Week 15

    ESPN+ • NFL

  • Taxi Squad (Ep. 7)

    ESPN+ • Peyton's Places

  • Boo-Yah: A Stuart Scott Portrait

    ESPN+

  • John Cena’s Final Round (Ep. 10)

    ESPN+ • WWE

  • Survivor Series: WarGames

    ESPN Unlimited • WWE

  • Maria Full of Strength

    ESPN+

  • Who Makes the Call? (Ep. 6)

    ESPN+ • Peyton's Places

  • Game On: Volleyball

    ESPN+ • NCAA Women's Volleyball

  • Football's Holy Grail (Ep. 5)

    ESPN+ • Peyton's Places

  • Final Finishers

    ESPN+ • Marathon

  • Miracles

    ESPN+ • ESPN Films

  • All Stars & All Americans (Ep. 10)

    ESPN+ • NCAA Football

  • BOOK I: DOUBT

    ESPN Unlimited • MLB

  • Thunder On: Resurgence of the SMU Mustangs

    ESPN+

  • Berlusconi: Condemned to Win (Part 1)

    ESPN Unlimited • 30 for 30

  • Above the Tide – 20 Years After Katrina

    ESPN+ • E60

Washington State vs. Utah State

Future Pac-12 members square off in Boise as both squads hope to finish 2025 with a winning record.

Famous Idaho Potato Bowl: Today, 2 p.m. ET

Leagues

  • NFL

  • NHL

  • NCAA Men's Basketball

  • NCAA Women's Basketball

  • NBA G League

  • NCAA Wrestling

  • NCAA Football

  • German Bundesliga

  • National Lacrosse League

  • NCAA Women's Volleyball

  • Spanish LALIGA

  • Spanish Copa del Rey

  • NCAA Men's Hockey

  • NCAA Women's Hockey

  • UFC

  • Professional Fighters League

  • NCAA Men's Soccer

  • NCAA Men's Water Polo

  • English FA Cup

  • German Cup

  • WWE

  • NBA

  • WNBA

  • NCAA Swimming & Diving

  • NCAA Track & Field

  • MLB

  • TGL

  • PGA TOUR

  • Mecum Auctions

  • American Cornhole League

  • X Games

  • NCAA

Sports

  • Basketball

  • Soccer

  • Hockey

  • Volleyball

  • Wrestling

  • Football

  • Lacrosse

  • MMA

  • Swimming and Diving

  • Track & Field

  • Golf

  • Cricket

  • Jai Alai

  • Field Hockey

  • Cross Country Running

  • Tennis

  • Rugby

  • Equestrian

  • Motor Sports

  • Baseball

Top Videos

See All

  • Jeanty takes it 51 yards to the house for his 2nd TD

  • Victor Wembanyama gets up for the beautiful flush

  • DK Metcalf shoves a fan during game in Detroit

  • Steelers prevail after offensive pass interference on dramatic final play

  • Crosby passes Lemieux as Penguins' all-time points leader

  • Drake Maye throws a dart to Kyle Williams for a TD

  • Zay Flowers' late turnover helps Pats seal comeback win

  • Hannah Hidalgo drops a 30-point triple-double for the Irish

  • Clayton Keller calls game with OT winner for Mammoth

  • Zay Flowers zooms in for a Ravens TD

  • Rickard Rakell's backhand goal wins the shootout for Pittsburgh

  • Rhamondre Stevenson runs in go-ahead TD for Pats

NFL PrimeTime

ESPN's Sunday evening NFL recap show, breaking down everything you might have missed, including the key highlights and biggest moments from each game.

Sundays at 7:30 p.m. ET on ESPN+

Conferences

  • Atlantic Coast Conference

  • Big Ten Conference

  • Big 12 Conference

  • Southeastern Conference

  • Pacific 12 Conference

  • American Conference

  • Big East Conference

  • Conference USA

  • Mid-American Conference

  • Mountain West Conference

  • Sun Belt Conference

  • America East Conference

  • ASUN Conference

  • Atlantic 10 Conference

  • Big Sky Conference

  • Big South Conference

  • Big West Conference

  • ECAC Hockey League

  • Hockey East

  • Horizon League

  • Ivy League

  • Metro Atlantic Athletic Conference

  • Mid-Eastern Athletic Conference

  • Missouri Valley Conference

  • Missouri Valley Football Conference

  • Northeast Conference

  • Ohio Valley Conference

  • Patriot League

  • Southern Conference

  • Southern Intercollegiate Athletic Conference

  • Southland Conference

  • Southwestern Athletic Conference

  • Summit League

  • West Coast Conference

  • Western Athletic Conference

Channels

SportsCenter

SportsCenter

ESPN • SportsCenter
NFL PrimeTime on ESPN+

NFL PrimeTime on ESPN+

ESPN+ • NFL
A Tall Tale (Ep. 8)

A Tall Tale (Ep. 8)

ESPN+ • Peyton's Places
#9 Alabama vs. #8 Oklahoma (First Round)

#9 Alabama vs. #8 Oklahoma (First Round)

SECN • RE-AIR • NCAA Football
Louisville vs. #2 Miami

Louisville vs. #2 Miami

ACCN • RE-AIR • NCAA Football
Cincinnati vs. Clemson

Cincinnati vs. Clemson

ESPNU • RE-AIR • NCAA Men's Basketball
USA Dodgeball All-Star Showcase

USA Dodgeball All-Star Showcase

ESPNews • RE-AIR • ESPN The Ocho
SEC Storied: The Book of Manning

SEC Storied: The Book of Manning

ESPN2 • RE-AIR • Football
SportsCenter

SportsCenter

ESPN Deportes • RE-AIR • ES • SportsCenter Noche
GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). Terms: sportsbook.draftkings.com/promos.
Copyright: © 2025 ESPN Enterprises, Inc. All rights reserved.