MNF: 49ers vs. Colts

The 49ers and Colts round out Week 16 as both teams look to continue their push for the playoffs.

Tonight at 8 p.m. ET

MNF Playbook with Next Gen Stats on ESPN2

Featured

  • North Carolina Central vs. #8 Oklahoma

    SECN+ • NCAA Women's Basketball

  • Temple vs. #25 Princeton

    ESPN+ • NCAA Women's Basketball

  • The Pat McAfee Show

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  • Mon, 12/22 - The Rich Eisen Show

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  • Fort Lauderdale vs. Florida Gulf Coast

    ESPN+ • NCAA Women's Basketball

  • Milligan vs. Miami (OH)

    ESPN+ • NCAA Men's Basketball

  • Defiance College vs. Western Michigan

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  • Northern Colorado vs. Sam Houston

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  • Trinity College of Jacksonville vs. Florida International

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  • Miami (OH)-Hamilton vs. Ohio

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  • NCAA Men's Basketball

    8 On Now

  • Defiance College vs. Western Michigan

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  • Trinity College of Jacksonville vs. Florida International

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  • Miami (OH)-Hamilton vs. Ohio

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  • Centenary (NJ) vs. Saint Peter's

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  • UMass Boston vs. Massachusetts

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  • St. Mary's College (MD) vs. George Washington

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  • New Haven vs. Fordham

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  • Milligan vs. Miami (OH)

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  • NCAA Women's Basketball

    7 On Now

  • Northern Colorado vs. Sam Houston

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  • Samford vs. UAB

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  • St. John's vs. Villanova

    ESPN+ • NCAA Women's Basketball

  • Gardner-Webb vs. Wake Forest

    ACCNX • NCAA Women's Basketball

  • North Carolina Central vs. #8 Oklahoma

    SECN+ • NCAA Women's Basketball

  • Temple vs. #25 Princeton

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  • Fort Lauderdale vs. Florida Gulf Coast

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Also Live

  • UFC 323: Dvalishvili vs. Yan 2 (Main Card)

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  • Motor City Cruise vs. College Park Skyhawks

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  • A Tall Tale (Ep. 8)

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  • First Take Presented by FreeStyle Libre

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  • Get Up Presented by FreeStyle Libre

    ESPNews • RE-AIR • Get Up!

  • #10 Miami vs. #7 Texas A&M (First Round)

    ACCN • RE-AIR • NCAA Football

  • #9 Alabama vs. #8 Oklahoma (First Round)

    SECN • RE-AIR • NCAA Football

  • Southern Hoops: A History of SEC Basketball Part Four (1980-1989) Presented by Pfizer

    ESPNU • RE-AIR • Basketball

  • En Español-Real Madrid vs. Sevilla FC

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Upcoming

See All

  • San Francisco 49ers vs. Indianapolis Colts

    ESPN/ESPN Deportes • EN/ES • NFL

  • MNF Playbook with Next Gen Stats: San Francisco 49ers vs. Indianapolis Colts

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  • Washington State vs. Utah State

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  • Bethune-Cookman vs. #1 Arizona

    ESPN+ • NCAA Men's Basketball

  • Eastern Washington vs. #10 BYU

    ESPN+ • NCAA Men's Basketball

  • Davidson vs. #17 Kansas

    ESPN+ • NCAA Men's Basketball

  • Southern Indiana vs. #17 Tennessee

    SECN+ • NCAA Women's Basketball

  • American University vs. #23 Virginia

    ACCN • NCAA Men's Basketball

  • West Georgia vs. #25 Georgia

    SECN+ • NCAA Men's Basketball

  • Athletic Club vs. RCD Espanyol

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  • Cleveland Cavaliers vs. New York Knicks

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  • New York Golf Club vs. Atlanta Drive GC

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  • Toledo vs. Louisville

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  • Western Kentucky vs. Southern Miss

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  • UNLV vs. Ohio

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  • California vs. Hawai'i

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  • Central Michigan vs. Northwestern

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  • New Mexico vs. Minnesota

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  • Florida International vs. UTSA

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  • Pittsburgh vs. East Carolina

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  • Penn State vs. Clemson

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  • UConn vs. Army

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  • #22 Georgia Tech vs. #12 BYU

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  • #25 North Texas vs. San Diego State

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  • #19 Virginia vs. Missouri

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  • LSU vs. #21 Houston

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  • Buffalo Bandits vs. Calgary Roughnecks

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  • NFL PrimeTime on ESPN+

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  • College Football Playoff Bowl

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  • College Football Playoff Bowl

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  • Prairie View vs. LSU

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  • East Carolina vs. #12 North Carolina

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  • Stetson vs. Oklahoma

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  • Providence vs. #3 South Carolina

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  • Wofford vs. Georgia Tech

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  • Stetson vs. Miami

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Recently Added

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  • NFL PrimeTime on ESPN+

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  • A Tall Tale (Ep. 8)

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  • Sat, 12/20 - #10 Miami vs. #7 Texas A&M (First Round)

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  • Fri, 12/19 - #9 Alabama vs. #8 Oklahoma (First Round)

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  • The Field Is Set (Ep. 1)

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  • NFL Turning Point: Week 15

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  • Taxi Squad (Ep. 7)

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  • Boo-Yah: A Stuart Scott Portrait

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  • John Cena’s Final Round (Ep. 10)

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  • Survivor Series: WarGames

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  • Maria Full of Strength

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  • Who Makes the Call? (Ep. 6)

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  • Game On: Volleyball

    ESPN+ • NCAA Women's Volleyball

  • Football's Holy Grail (Ep. 5)

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  • Final Finishers

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  • All Stars & All Americans (Ep. 10)

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  • BOOK I: DOUBT

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  • Thunder On: Resurgence of the SMU Mustangs

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  • Berlusconi: Condemned to Win (Part 1)

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  • Above the Tide – 20 Years After Katrina

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Washington State vs. Utah State

Future Pac-12 members square off in Boise as both squads hope to finish 2025 with a winning record.

Famous Idaho Potato Bowl: Today, 2 p.m. ET

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Top Videos

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  • Cam Newton blames Jerry Jones for the state of the Cowboys

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  • Orlovsky: Trevor Lawrence is the NFL's most improved player

  • Cam Newton delivers a message to Bama fans and Kalen DeBoer

  • Orlovsky: Ravens are most disappointing team this season

  • Schefter: DK Metcalf likely to face suspension after fan altercation

  • Can Bears make a Super Bowl run this season?

  • Why Foxworth isn't ready to close the window on the Lions

  • DK Metcalf shoves a fan during game in Detroit

  • Steelers prevail after offensive pass interference on dramatic final play

NFL PrimeTime

ESPN's Sunday evening NFL recap show, breaking down everything you might have missed, including the key highlights and biggest moments from each game.

Sundays at 7:30 p.m. ET on ESPN+

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Channels

North Carolina Central vs. #8 Oklahoma

North Carolina Central vs. #8 Oklahoma

SECN+ • NCAA Women's Basketball
Temple vs. #25 Princeton

Temple vs. #25 Princeton

ESPN+ • NCAA Women's Basketball
The Pat McAfee Show

The Pat McAfee Show

ESPN/ESPN+ • The Pat McAfee Show
Mon, 12/22 - The Rich Eisen Show

Mon, 12/22 - The Rich Eisen Show

ESPN+ • The Rich Eisen Show
Fort Lauderdale vs. Florida Gulf Coast

Fort Lauderdale vs. Florida Gulf Coast

ESPN+ • NCAA Women's Basketball
Milligan vs. Miami (OH)

Milligan vs. Miami (OH)

ESPN+ • NCAA Men's Basketball
Defiance College vs. Western Michigan

Defiance College vs. Western Michigan

ESPN+ • NCAA Men's Basketball
Northern Colorado vs. Sam Houston

Northern Colorado vs. Sam Houston

ESPN+ • NCAA Women's Basketball
Trinity College of Jacksonville vs. Florida International

Trinity College of Jacksonville vs. Florida International

ESPN+ • NCAA Men's Basketball
Miami (OH)-Hamilton vs. Ohio

Miami (OH)-Hamilton vs. Ohio

ESPN+ • NCAA Men's Basketball
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