MNF: Panthers vs. 49ers

The Panthers and 49ers square off in prime-time as both teams continue their push for the playoffs.

Coverage begins at 8:15 p.m. ET

MNF with Peyton and Eli on ESPN2

Featured

  • Unsportsmanlike with Evan, Canty and Michelle Presented by Progressive

    ESPN2/ESPNU • Unsportsmanlike with Evan, Canty and Michelle

  • Lies, Damned Lies and Football Statistics (Ep. 4)

    ESPN+ • Peyton's Places

  • SportsCenter

    ESPN • RE-AIR • SportsCenter

  • ACC Huddle Final Score

    ACCN • RE-AIR • NCAA Football

  • SEC Inside: Texas vs. Georgia

    SECN • RE-AIR • NCAA Football

  • SEC Storied: The Play That Changed College Football

    ESPNews • RE-AIR • SEC Storied

  • Fútbol Picante

    ESPN Deportes • RE-AIR • ES • Futbol Picante Noche

Also Live

  • Fútbol Picante

    ESPN Deportes • RE-AIR • ES • Futbol Picante Noche

Upcoming

See All

  • Carolina Panthers vs. San Francisco 49ers

    ESPN/ESPN Deportes • EN/ES • NFL

  • MNF with Peyton and Eli: Carolina Panthers vs. San Francisco 49ers

    ESPN2 • NFL

  • Eastern Michigan vs. #6 Louisville

    ACCN • NCAA Men's Basketball

  • Longwood vs. #13 Ole Miss

    SECN+ • NCAA Women's Basketball

  • Texas A&M-Corpus Christi vs. #18 Oklahoma State

    ESPN+ • NCAA Women's Basketball

  • 2025 U.S. Virgin Islands Paradise Jam (Championship)

    ESPN+ • NCAA Men's Basketball

  • Central Michigan vs. #24 Notre Dame

    ACCN • NCAA Women's Basketball

  • Seton Hall vs. #25 NC State

    ESPN2 • NCAA Men's Basketball

  • Detroit Pistons vs. Boston Celtics

    ESPN/ESPN Unlimited • EN/ES • NBA

  • Minnesota Timberwolves vs. Oklahoma City Thunder

    ESPN/ESPN Unlimited • EN/ES • NBA

  • Houston Rockets vs. Golden State Warriors

    ESPN/ESPN Unlimited • EN/ES • NBA

  • #6 Ole Miss vs. Mississippi State

    ESPN on ABC/ESPN3 • NCAA Football

  • #4 Georgia vs. #16 Georgia Tech

    ESPN on ABC/ESPN3 • EN/ES • NCAA Football

  • #3 Texas A&M vs. #17 Texas

    ESPN on ABC/ESPN3 • EN/ES • NCAA Football

  • Navy vs. Memphis

    ESPN • NCAA Football

  • #12 Utah vs. Kansas

    ESPN • NCAA Football

  • Temple vs. North Texas

    ESPN • NCAA Football

  • #13 Miami vs. Pittsburgh

    ESPN on ABC/ESPN3 • NCAA Football

  • #5 Texas Tech vs. West Virginia

    ESPN • NCAA Football

  • Vanderbilt vs. Tennessee

    ESPN • NCAA Football

  • LSU vs. #8 Oklahoma

    ESPN on ABC/ESPN3 • NCAA Football

  • Virginia Tech vs. #19 Virginia

    ESPN • NCAA Football

  • #10 Alabama vs. Auburn

    ESPN on ABC/ESPN3 • NCAA Football

  • #9 Notre Dame vs. Stanford

    ESPN • NCAA Football

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN • NCAA Men's Basketball

  • Western Michigan vs. Eastern Michigan

    ESPN2 • NCAA Football

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN • NCAA Men's Basketball

  • #19 UCLA vs. California

    ESPN • NCAA Men's Basketball

  • Vanderbilt vs. Western Kentucky

    ESPN • NCAA Men's Basketball

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (Championship)

    ESPN • NCAA Men's Basketball

  • Marriott Bonvoy Battle 4 Atlantis as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN • NCAA Men's Basketball

  • Marriott Bonvoy Battle 4 Atlantis as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN • NCAA Men's Basketball

  • #9 BYU vs. Miami

    ESPN • NCAA Men's Basketball

  • Ohio State vs. Pittsburgh

    ESPN • NCAA Men's Basketball

  • Terry's Chocolate ESPN Events Invitational - Magic Bracket as part of Feast Week Presented by Lowe's (Championship)

    ESPN • NCAA Men's Basketball

  • UCF vs. #11 BYU

    ESPN2 • NCAA Football

  • Florida State vs. Florida

    ESPN2 • NCAA Football

  • SMU vs. California

    ESPN2 • NCAA Football

  • Rhode Island vs. Towson

    ESPN2 • NCAA Men's Basketball

  • USC vs. Boise State

    ESPN2 • NCAA Men's Basketball

  • Arizona State vs. Texas

    ESPN2 • NCAA Men's Basketball

  • Terry's Chocolate ESPN Events Invitational - Adventure Bracket as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN2 • NCAA Men's Basketball

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (Consolation Game)

    ESPN2 • NCAA Men's Basketball

  • Terry's Chocolate ESPN Events Invitational - Adventure Bracket as part of Feast Week Presented by Lowe's (Semifinal)

    ESPN2 • NCAA Men's Basketball

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (Consolation Game)

    ESPN2 • NCAA Men's Basketball

  • Terry's Chocolate ESPN Events Invitational - Adventure Bracket as part of Feast Week Presented by Lowe's (Championship)

    ESPN2 • NCAA Men's Basketball

  • VCU vs. South Florida

    ESPN2 • NCAA Men's Basketball

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (3rd Place Game)

    ESPN2 • NCAA Men's Basketball

  • Saint Mary's vs. Wichita State

    ESPN2 • NCAA Men's Basketball

  • The Southwest Maui Invitational as part of Feast Week Presented by Lowe's (5th Place Game)

    ESPN2 • NCAA Men's Basketball

Recently Added

See All

  • Lies, Damned Lies and Football Statistics (Ep. 4)

    ESPN+ • Peyton's Places

  • Sat, 11/22 - Formula 1 Heineken Las Vegas Grand Prix

    ESPN • Formula One

  • Sun, 11/23 - College Football Final

    ESPN2 • RE-AIR • NCAA Football

  • NFL Turning Point: Week 11

    ESPN+ • NFL

  • The Harbaugh Files (Ep. 3)

    ESPN+ • Peyton's Places

  • Sneak Attack! (Ep. 2)

    ESPN+ • Peyton's Places

  • Final Finishers

    ESPN+ • Marathon

  • Miracles

    ESPN+ • ESPN Films

  • UFC 321: Aspinall vs. Gane (Main Card)

    ESPN+ • UFC

  • The Bills Mafia (Ep. 1)

    ESPN+ • Peyton's Places

  • All Stars & All Americans (Ep. 10)

    ESPN+ • NCAA Football

  • The Man in the Suit (Ep. 9)

    ESPN+ • NCAA Football

  • Welcome to the NHL: Class of 2025

    ESPN+ • NHL

  • Crown Jewel

    ESPN Unlimited • WWE

  • The Pirate (Ep. 8)

    ESPN+ • NCAA Football

  • 2025 Stanley Cup Championship Film

    ESPN+ • NHL

  • Think Fast, Act Fast (Ep. 7)

    ESPN+ • NCAA Football

  • BOOK I: DOUBT

    ESPN Unlimited • MLB

  • The Many Lives of Lane Kiffin

    ESPN+ • Football

  • John Cena’s Final Round (Ep. 10)

    ESPN+ • WWE

  • Thunder On: Resurgence of the SMU Mustangs

    ESPN+

  • Berlusconi: Condemned to Win (Part 1)

    ESPN Unlimited • 30 for 30

  • Who Is Stan Smith?

    ESPN+ • Tennis

  • Not So Fast, My Friend: A Lee Corso Special

    ESPN+ • NCAA Football

  • Big Dreams: Little League World Series 2024

    ESPN+

  • Above the Tide – 20 Years After Katrina

    ESPN+ • E60

  • Wishbone

    ESPN+ • NCAA Football

  • Southpaw – The Life and Legacy of Jim Abbott

    ESPN+ • Baseball

Peyton's Places

Peyton Manning visits some of the NFL’s most important places and experiences some of football’s most magical moments.

New episodes Sundays

Leagues

  • NFL

  • NHL

  • NCAA Men's Basketball

  • NCAA Women's Basketball

  • WNBA

  • NCAA Men's Soccer

  • NCAA Women's Soccer

  • NCAA Women's Volleyball

  • NCAA Tennis

  • NCAA Field Hockey

  • LPGA

  • German Bundesliga

  • Spanish LALIGA

  • NCAA Football

  • NCAA Women's Hockey

  • NCAA Men's Hockey

  • Formula One

  • NCAA Men's Water Polo

  • UFC

  • NCAA Cross Country

  • PGA TOUR

  • NBA G League

  • NBA

  • NCAA Wrestling

  • NCAA Swimming & Diving

  • MLB

  • WWE

  • National Lacrosse League

  • Professional Fighters League

  • Mecum Auctions

  • American Cornhole League

  • X Games

  • NCAA

Sports

  • Soccer

  • Basketball

  • Football

  • Hockey

  • Field Hockey

  • Volleyball

  • MMA

  • Motor Sports

  • Golf

  • Cross Country Running

  • Swimming and Diving

  • Wrestling

  • Tennis

  • Rugby

  • Cricket

  • Jai Alai

  • Equestrian

  • Baseball

  • Softball

  • Lacrosse

  • Fishing

Top Videos

See All

  • Luka flirts with triple-double in 33-point game for Lakers

  • LeBron glides in for a big Lakers dunk

  • Shedeur slings first career TD pass

  • Messi does it all with 1 goal, 3 assists in Inter Miami win

  • Aaron Donald pumped up after Jared Verse's sack

  • Luka Doncic nutmegs Kevin Love en route to alley-oop assist

  • Maxi Morález slots in the goal for New York City FC

  • Top-seeded Vermont's title defense ends with OT loss to Hofstra

  • Audi Crooks drops 27 in Iowa State's win

  • Baker Mayfield shaken up after TD pass

  • Shedeur Sanders' 52-yard pass sets up Quinshon Judkins' 2nd TD

  • Arrinten Page wins it for Northwestern as time expires

NFL PrimeTime

ESPN's Sunday evening NFL recap show, breaking down everything you might have missed, including the key highlights and biggest moments from each game.

Sundays at 7:30 p.m. ET on ESPN+

Conferences

  • Atlantic Coast Conference

  • Big Ten Conference

  • Big 12 Conference

  • Southeastern Conference

  • Pacific 12 Conference

  • American Conference

  • Big East Conference

  • Conference USA

  • Mid-American Conference

  • Mountain West Conference

  • Sun Belt Conference

  • America East Conference

  • ASUN Conference

  • Atlantic 10 Conference

  • Big Sky Conference

  • Big South Conference

  • Big West Conference

  • ECAC Hockey League

  • Hockey East

  • Horizon League

  • Ivy League

  • Metro Atlantic Athletic Conference

  • Mid-Eastern Athletic Conference

  • Missouri Valley Conference

  • Missouri Valley Football Conference

  • Northeast Conference

  • Ohio Valley Conference

  • Patriot League

  • Southern Conference

  • Southern Intercollegiate Athletic Conference

  • Southland Conference

  • Southwestern Athletic Conference

  • Summit League

  • West Coast Conference

  • Western Athletic Conference

Channels

Unsportsmanlike with Evan, Canty and Michelle Presented by Progressive

Unsportsmanlike with Evan, Canty and Michelle Presented by Progressive

ESPN2/ESPNU • Unsportsmanlike with Evan, Canty and Michelle
Lies, Damned Lies and Football Statistics (Ep. 4)

Lies, Damned Lies and Football Statistics (Ep. 4)

ESPN+ • Peyton's Places
SportsCenter

SportsCenter

ESPN • RE-AIR • SportsCenter
ACC Huddle Final Score

ACC Huddle Final Score

ACCN • RE-AIR • NCAA Football
SEC Inside: Texas vs. Georgia

SEC Inside: Texas vs. Georgia

SECN • RE-AIR • NCAA Football
SEC Storied: The Play That Changed College Football

SEC Storied: The Play That Changed College Football

ESPNews • RE-AIR • SEC Storied
Fútbol Picante

Fútbol Picante

ESPN Deportes • RE-AIR • ES • Futbol Picante Noche
ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN'). ESPN BET is available in states where PENN is licensed to offer sports wagering. Must be 21+ to wager. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.
Copyright: © 2025 ESPN Enterprises, Inc. All rights reserved.