49ers face the Buccaneers in a matchup of 4-1 teams playing well despite injuries

— The San Francisco 49ers and Tampa Bay Buccaneers are winning despite a slew of injuries to key players.
Oct 9, 2025, 05:41 pm - AP
Game Odds
2025-10-12T20:25ZOpenSpreadTotalML
San Francisco 49ers49ersSF
(4-1)
(4-1, 3-0 Away)
o46.5
-115
+3.5
-130
o47.5
-105
+145
Tampa Bay BuccaneersBuccaneersTB
(4-1)
(4-1, 1-1 Home)
-2.5
-120
-3.5
+110
u47.5
-115
-170

Season Leaders

49ersBuccaneers
Mac Jones
905
M. JonesQBQ
86/129, 6 TD, 1 INT
905
Passing Yards
Baker Mayfield
1,283
B. MayfieldQB
112/172, 10 TD, 1 INT
1,283
Christian McCaffrey
282
C. McCaffreyRB
91 CAR
282
Rushing Yards
Bucky Irving
237
B. IrvingRBO
71 CAR
237
Christian McCaffrey
387
C. McCaffreyRB
39 REC, 3 TD
387
Receiving Yards
Emeka Egbuka
445
E. EgbukaWR
25 REC, 5 TD
445
Bryce Huff
3
B. HuffDE
3
Sacks
Vita Vea
2
V. VeaDT
2
Fred Warner
50
F. WarnerLB
50
Tackles
Tykee Smith
39
T. SmithS
39

Injury Report

San Francisco 49ers
NameStatusEst. Return
Alfred CollinsA. CollinsDT
QuestionableKnee
Oct 12
Jordan WatkinsJ. WatkinsWR
QuestionableCalf
Oct 12
Jauan JenningsJ. JenningsWR
QuestionableAnkle
Oct 12
Mac JonesM. JonesQB
QuestionableKnee
Oct 12
Ricky PearsallR. PearsallWR
QuestionableKnee - PCL
Oct 12
Tampa Bay Buccaneers
NameStatusEst. Return
Bucky IrvingB. IrvingRB
OutShoulder
Oct 20
Josh WilliamsJ. WilliamsRB
OutConcussion
Oct 20
Chris Godwin Jr.C. Godwin Jr.WR
OutLower Leg
Oct 20
Jalen McMillanJ. McMillanWR
IR-RNeck
Oct 12
Benjamin MorrisonB. MorrisonCB
DoubtfulHamstring
Oct 12

LAST FIVE GAMES

49ers
DATEOPPRESULT
10/2/25@LARW26-23 OT
9/28/25vsJAXL26-21
9/21/25vsARIW16-15
9/14/25@NOW26-21
9/7/25@SEAW17-13
Buccaneers
DATEOPPRESULT
10/5/25@SEAW38-35
9/28/25vsPHIL31-25
9/21/25vsNYJW29-27
9/15/25@HOUW20-19
9/7/25@ATLW23-20
Data is currently unavailable.