San Francisco 49ers @ Buffalo Bills
Game Leaders

94
B. PurdyQB
11/18
94

148
J. AllenQB
13/17, 2 TD
148

78
J. MasonRB
13 CAR
78

107
J. CookRB
14 CAR, 1 TD
107

56
J. JenningsWR
3 REC
56

56
D. KnoxTE
2 REC
56

--
--

1
G. RousseauDE
1

8
J. BrownS
4 SOLO
8

9
T. BernardLB
3 SOLO
9
Team Stats
239
Total Yards
372
3
Turnovers
0
15
1st Downs
20
2-10
Penalties
5-35
3/10
3rd Down
6/12
1/1
4th Down
1/1
1/3
Red Zone
4/4
26:33
Possession
33:27
Game Information
Orchard Park, NY

NBCPeacock
Line Judge:Rusty Baynes
Field Judge:Sean Petty
Back Judge:Scott Helverson
Referee:Alex Kemp
Umpire:Mike Morton
Side Judge:Lo van Pham
Down Judge:Robert Richeson

Betting Results
OpenSpreadTotalML


o45.5
-115
+6.5
-110

o44.5
-125
+240
-6.5
-105

-6.5
-110
u44.5
+102

-290
1st Quarter

Field Goal
7:41 - 1st
3
SF
0
BUF
Jake Moody 33 Yd Field Goal
9 plays, 48 yards, 4:40

Touchdown
0:03 - 1st
3
SF
7
BUF
Ray Davis 5 Yd Rush (Tyler Bass Kick)
13 plays, 70 yards, 7:38
2nd Quarter

Touchdown
8:38 - 2nd
3
SF
14
BUF
James Cook 65 Yd Rush (Tyler Bass Kick)
1 play, 65 yards, 0:10

Touchdown
0:41 - 2nd
3
SF
21
BUF
Mack Hollins 7 Yd pass from Josh Allen (Tyler Bass Kick)
9 plays, 97 yards, 2:50
3rd Quarter

Touchdown
5:58 - 3rd
3
SF
28
BUF
Amari Cooper pass from Josh Allen, lateral to Josh Allen for 7 Yd Touchdown (Tyler Bass Kick)
6 plays, 44 yards, 3:05

Touchdown
2:54 - 3rd
10
SF
28
BUF
Isaac Guerendo 15 Yd Rush (Jake Moody Kick)
6 plays, 48 yards, 3:04
4th Quarter

Touchdown
12:31 - 4th
10
SF
35
BUF
Josh Allen 8 Yd Rush (Tyler Bass Kick)
4 plays, 25 yards, 2:22
Data is currently unavailable.
Win Probability
0%
--SF
100%
--BUF
According to ESPN Analytics
2025 Standings
National Football Conference
NFC West | W | L | T | PCT | PF | PA |
---|---|---|---|---|---|---|
San Francisco | 2 | 0 | 0 | 1.000 | 43 | 34 |
Arizona | 2 | 0 | 0 | 1.000 | 47 | 35 |
Los Angeles | 2 | 0 | 0 | 1.000 | 47 | 28 |
Seattle | 1 | 1 | 0 | .500 | 44 | 34 |
American Football Conference
AFC East | W | L | T | PCT | PF | PA |
---|---|---|---|---|---|---|
Buffalo | 2 | 0 | 0 | 1.000 | 71 | 50 |
New England | 1 | 1 | 0 | .500 | 46 | 47 |
New York | 0 | 2 | 0 | .000 | 42 | 64 |
Miami | 0 | 2 | 0 | .000 | 35 | 66 |
NFL News

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