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    Odds by

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    AFC South Division Winner

    TEAMODDS
    Indianapolis ColtsIND-350
    Jacksonville JaguarsJAX+375
    TEAMODDS
    Houston TexansHOU+1400

    AFC North Division Winner

    TEAMODDS
    Baltimore RavensBAL-300
    Pittsburgh SteelersPIT+250
    TEAMODDS
    Cincinnati BengalsCIN+4000
    Cleveland BrownsCLE+30000

    AFC West Division Winner

    TEAMODDS
    Denver BroncosDEN-300
    Kansas City ChiefsKC+500
    TEAMODDS
    Los Angeles ChargersLAC+600
    Las Vegas RaidersLV+50000

    AFC East Division Winner

    TEAMODDS
    New England PatriotsNE-250
    Buffalo BillsBUF+200
    TEAMODDS
    Miami DolphinsMIA+50000
    New York JetsNYJ+50000

    NFC North Division Winner

    TEAMODDS
    Detroit LionsDET+135
    Green Bay PackersGB+140
    TEAMODDS
    Chicago BearsCHI+350
    Minnesota VikingsMIN+7500

    NFC East Division Winner

    TEAMODDS
    Philadelphia EaglesPHI-10000
    Dallas CowboysDAL+5000
    TEAMODDS
    New York GiantsNYG+30000
    Washington CommandersWSH+30000

    NFC West Division Winner

    TEAMODDS
    Los Angeles RamsLAR-225
    Seattle SeahawksSEA+275
    TEAMODDS
    San Francisco 49ersSF+750
    Arizona CardinalsARI+30000

    NFC South Division Winner

    TEAMODDS
    Tampa Bay BuccaneersTB-800
    Carolina PanthersCAR+550
    TEAMODDS
    Atlanta FalconsATL+10000
    New Orleans SaintsNO+30000
    Looking for odds for this week’s NFL?
    NFL Odds - Week 12

    Odds by

    2025-11-21T01:15ZOpenSpreadTotalML
    Buffalo BillsBillsBUF
    (7-3)
    (7-3, 5-1 Away)
    -3.5
    -110
    -6
    -115
    o43.5
    -110
    -280
    Houston TexansTexansHOU
    (5-5)
    (5-5, 3-2 Home)
    u44.5
    -110
    +6
    -105
    u43.5
    -110
    +230
    2025-11-23T18:00ZOpenSpreadTotalML
    Indianapolis ColtsColtsIND
    (8-2)
    (8-2, 6-0 Away)
    o50.5
    -110
    +3.5
    -120
    o49.5
    -115
    +160
    Kansas City ChiefsChiefsKC
    (5-5)
    (5-5, 4-1 Home)
    -3.5
    -110
    -3.5
    EVEN
    u49.5
    -105
    -190
    See More NFL Odds

    NFL News

    2026 NFL mock drafts: Latest ESPN player, team predictions

    2026 NFL mock drafts: Latest ESPN player, team predictions

    Here are our experts' NFL mock drafts for the 2026 cycle, including projected landing spots for all the top quarterbacks.
    2026 NFL mock draft: Miller's first-round pick predictions

    2026 NFL mock draft: Miller's first-round pick predictions

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    NFL Week 12 latest buzz, questions, news and fantasy tips

    NFL Week 12 latest buzz, questions, news and fantasy tips

    Will Joe Burrow and Jayden Daniels play again this season? Are the Vikings worried about J.J. McCarthy? And which coaches are on the hot seat? Here's what we're hearing.
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