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Men's March Madness 2025: Final Four betting odds, lines, totals and BPI

Betting, Men's College Basketball, Auburn Tigers, Houston Cougars, Florida Gators, Duke Blue Devils

The 2025 men's NCAA tournament began with 68 teams looking to raise a banner and write their name into college basketball history. The Auburn Tigers, the overall No. 1 seed in the South, are looking to avenge their SEC tournament loss and claim the title as the best team in the country, but they'll face stiff competition from tournament favorites Duke and Florida as well as from fellow No. 1 seed Houston.

For the first time since 2008, all four top seeds have made it to the Final Four and will face off to see who will compete for the championship.

Here are the lines for both of Saturday's Final Four matchups, with the winners facing off on Monday, April 5 for the chance to cut down the nets at the Alamodome in San Antonio, Texas.

Odds are accurate as of publication time. All times Eastern. For the latest odds, go to ESPN BET.

Saturday


(1) Florida Gators -2.5
(1) Auburn Tigers

West Region, 6:09 p.m., Alamodome, San Antonio, Texas


Florida: 29-4, 14-4 in SEC play
Auburn: 28-5, 15-3 in SEC play

Odds by ESPN BET Moneyline: Florida (-155), Auburn (+130) Total: 159.5

BPI Projection: Auburn by 2, straight up: 57.9%


(1) Houston Cougars
(1) Duke Blue Devils -5.5

East Region, 8:49 p.m., Alamodome, San Antonio, Texas


Houston: 30-4, 19-1 in Big 12 play
Duke: 31-3, 19-1 in ACC play

Odds by ESPN BET Moneyline: Duke (-260), Houston (+215) Total: 135.5

BPI Projection: Duke by 1, straight up: 54%

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