Pakistan won the toss and decided to bat against England
Live scorecard and ball-by-ball details
With the series decided, both England and Pakistan have taken the opportunity to rotate their sides, but from vastly different positions of strength, while Pakistan won the toss and opted to bat first at Headingley.
England have made three changes, including a switch in wicketkeeper with Jonny Bairstow replacing Jos Buttler who suffered an injury in the warm-ups, with Chris Jordan and David Willey coming into a re-jigged pace attack as Chris Woakes and Mark Wood are rested.
It means a strengthened Yorkshire contingent on their home ground with Bairstow and Willey making their first appearances of the series alongside the incumbent White Rose trio of Joe Root, Liam Plunkett and Adil Rashid.
A shell-shocked Pakistan, having conceded a world-record 444 for 3 two days ago, have made four changes. Imad Wasim returns having been injured for Trent Bridge, coming in for the experienced Shoaib Malik who has had a poor series, while Umar Gul, Mohammad Rizwan and Mohammad Irfan are drafted in.
Mohammad Amir, Yasir Shah and Wahab Riaz - the latter who conceded none for 110 at Trent Bridge, the second-worst figures in ODI history - are the bowlers making way.
England 1 Jason Roy, 2 Alex Hales, 3 Joe Root, 4 Eoin Morgan (capt), 5 Ben Stokes, 6 Jonny Bairstow (wk), 7 Moeen Ali, 8 Adil Rashid, 9 Liam Plunkett, 10 Chris Jordan, 11 David Willey
Pakistan 1 Sami Aslam, 2 Sharjeel Khan, 3 Azhar Ali (capt), 4 Babar Azam, 5 Sarfraz Ahmed (wk), 6 Mohammad Rizwan, 7 Mohammad Nawaz, 8 Imad Wasim, 9 Hasan Ali, 10 Umar Gul, 11 Mohammad Irfan